Incidence of health care-associated infections in high-risk hospital units

Goloverova, Yu.А.; Maryin, G. G.; Shabalina, S.V.; Tutelyan, A.V.; Орлова, О. А.; Акимкин, В. Г.

doi:10.20953/1729-9225-2019-3-69-73

Cited by 5 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Тем не менее эта ситуация оказала существенное влияние на ускорение темпов селекции штаммов бактерий с множественной лекарственной устойчивостью [3]. Она также обострила проблему инфекций, связанных с оказанием медицинской помощи (ИСМП), в частности проблему распространения устойчивых штаммов внутри стационаров с возможным развитием нозокомиальных инфекций [4,5].…”

unclassified

Comparative Analysis of Bacterial Microflora Isolated from Adult Pneumonia Inpatients and Hospital Objects in the Amur Region

Bondarenko¹,

Курганова²,

Троценко³

et al. 2022

PH&LE

View full text Add to dashboard Cite

Background: The COVID-19 pandemic has exacerbated the problem of healthcare-associated infections and worsened the situation with the hospital spread of antibiotic resistant strains potentially inducing nosocomial infections. Objective: To compare bacterial microflora isolated from adult pneumonia inpatients and hospital objects and to assess the risk of hospital-acquired infections in the Amur Region. Materials and methods: The study was conducted in a multidisciplinary and a “COVID” hospital hereinafter referred to as Hospitals 1 and 2, respectively. Parallel bacteria culture testing of 519 sputum samples from 284 inpatients and 486 wipe samples collected weekly during 12 weeks in both hospitals was carried out using a classical method. AutoSCAN-4 and Vitek® 2 Compact 30 analyzers were applied to identify pathogens and determine their antimicrobial susceptibility. Results: Along with the detection of pathogenic bacteria in 33.8 % of hospitalized patients with pneumonia, we found pathogens in 23.3 % and 12.4 % of wipe samples from Hospitals 1 and 2, respectively, and established that the proportion of Gram-negative bacteria in them was 44.9 % and 15.4 % while the share of multidrug-resistant strains was 32.7 % and 3.8 %. The significant differences observed can be attributed to a more stringent disinfection regime in Hospital 2. The structure of multidrug-resistant Gram-negative bacteria was noted for a high proportion of carbapenem-resistant organisms isolated from both sputum (20.0 %) and wipe (38.9 %) samples. Conclusion: Our monitoring results helped define the composition and ratio of bacterial pathogens isolated from pneumonia cases and hospital objects. A wide range of pathogens, including those resistant to antibiotics, often detected in wipe samples and their accumulation over time indicate the potential hazard of the hospital environment posing an increased risk of hospital-acquired infections.

show abstract

unclassified

Comparative Analysis of Bacterial Microflora Isolated from Adult Pneumonia Inpatients and Hospital Objects in the Amur Region

Bondarenko¹,

Курганова²,

Троценко³

et al. 2022

PH&LE

View full text Add to dashboard Cite

show abstract

Evaluation of the two in-patient hospitals on potential environmental hazard during the period of new coronavirus infection in the Khabarovsk city (december 2020 — march 2021)

Троценко

Bondarenko

Pshenichnaya

et al. 2022

Russian Journal of Infection and Immunity

View full text Add to dashboard Cite

Abstract. Microbiological monitoring after infectious diseases in the system of epidemiological surveillance implies simultaneous pathogen identification both among patients as well as in hospital environment. Objective. To assess potential hospital environmental hazard for the two in-patient infectious disease hospitals of the Khabarovsk city by using bacteriological and epidemiological analysis during new coronavirus disease pandemic. Materials and methods. Bacteriological assessment of nasopharyngeal microflora in 241 patients suffering from community-acquired pneumonia that were hospitalized in the two medical-prophylactic institutions of the Khabarovsk city was performed. Sanitary-bacteriological control of hospital environment (428 hospital environment samples and 91 air samples) was carried out in parallel. Bacteriological assessment was performed with classical methods. Identification of isolated bacteriological pathogens and evaluation of drug-resistant strains were carried out by utilizing bacteriological analyzer Vitec 2 Compact. Results. Nine different pathogens (Psuedomonas aeruginosa, Pseudomonas stutzeri, Acinetobacter baumannii, Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter cloacae, Pantoea, Enterococcus faecium, Staphylococcus haemolyticus) were isolated in 20 out of 428 samples – 4.7% [2.7–6.7]. Half of isolated agents – 2.3% [0.9–3.8] were represented by drug-resistant isolates (10 out of 20 isolates) including 5 carbapenem-resistant isolates (Acinetobacter baumannii, Psuedomonas aeruginosa, Klebsiella pneumoniae) and 5 isolates with multiple drug resistance (Enterobacter cloacae, Pantoea, Enterococcus faecium, Staphylococcus haemolyticus). Air samples contained pathogenic biological agents found in 6 out of 91 samples – 6.6% [1.5–11.7], and half of them – 3.3% [0.6–7.9] were identified as drug-resistant variants – including S. aureus и S. haemolyticus. One of the surveyed hospitals was recognized as more hazardous due to microflora isolated from intensive care unit (A. baumannii and P. aeruginosa were resistant to 3rd – 4th generation cephalosporins and carbapenems). Conclusion. Revealed circulation of wide range of microorganisms isolated from environment of two in-patient hospitals indicates high risk of healthcare-associated infections formation. Intensive care units can serve as a reservoir of healthcare-associated infections due to high percentage of patients with severe disease cases (“main reservoir” of drug-resistant strains).

show abstract

Characteristics of Bacterial Microflora Isolated from Sputum of Patients with Pneumonia Registered in Khabarovsk City and Khabarovsk Territory in the Initial Period of COVID-19 Pandemic in May–June, 2020

Bondarenko

Шмыленко

Троценко

et al. 2020

Problemy Osobo Opasnykh Infektsii

View full text Add to dashboard Cite

Objective: to study the bacterial microflora in the sputum of patients with pneumonia caused by SARSCoV-2 or other pathogens.Materials and methods. The bacterial microflora of sputum of 173 patients with pneumonia admitted to hospitals in Khabarovsk and the Khabarovsk Territory in May – June 2020 was examined. Detection of RNA of the SARS-CoV-2 virus was carried out by PCR with the Vector-PCRRV-2019-nCoV-RG test system (manufactured by the State Scientific Center of VB “Vector”, Koltsovo). Determination of the DNA of mycoplasmosis agents and chlamydia was carried out with the test system “AmpliSens® Mycoplasma pneumoniae/Chlamydophila pneumonia” (manufactured by CRIE). Statistical data processing was performed using the Excel program. Results and discussion. Both groups of patients (Covid-19+ and Covid-19–) had high levels of bacterial flora isolation (81.4 and 74.7 %) including common pathogens for community-acquired pneumonia as well as notable detection frequency of Candida spp. and microbial associations. The group of Covid-19+ patients demonstrated a wider range of detected pathogens, was positive for poly-resistant gram-negative Enterobacteriaceae, non-fermenting gram-negative poly-resistant bacteria, with more expressed manifestation of microbial associations. In the group of Covid-19– participants drug-resistant microflora was presented only by MRSA and MRSE staphylococci.

show abstract

Incidence of health care-associated infections in high-risk hospital units

Cited by 5 publications

References 0 publications

Comparative Analysis of Bacterial Microflora Isolated from Adult Pneumonia Inpatients and Hospital Objects in the Amur Region

Comparative Analysis of Bacterial Microflora Isolated from Adult Pneumonia Inpatients and Hospital Objects in the Amur Region

Evaluation of the two in-patient hospitals on potential environmental hazard during the period of new coronavirus infection in the Khabarovsk city (december 2020 — march 2021)

Characteristics of Bacterial Microflora Isolated from Sputum of Patients with Pneumonia Registered in Khabarovsk City and Khabarovsk Territory in the Initial Period of COVID-19 Pandemic in May–June, 2020

Contact Info

Product

Resources

About