“…Our group have published several studies both on stored extracted teeth and on teeth from cadavers using nondestructive micro-CT evaluation, and all of them convey the same conclusion: no new microcracks were induced by root canal Letter to the Editor International Endodontic Journal, 53,[137][138][139][140][141][142]2020 instrumentation or canal filling (De-Deus et al 2014, 2015,b, Zuolo et al 2017. Moreover, there are other studies using micro-CT confirming that root dentinal microcracks are not related to mechanical shaping of the canal (Bayram et al 2017a,b, Oliveira et al 2017, R€ odig et al 2019, U gur Aydın et al 2019. Taken together, these reproducible micro-CT outcomes largely contrast with the results of previous cross-sectioning studies and therefore provide strong evidence to support the rationale of our conclusion.…”