Incidence of Rh Antigens, Phenotype &amp; Probable Genotype in the Population of Gwalior and Chambal Region, Central India

Sharma, Dharmesh Chandra; Singhal, Sachin; Rai, Sunita; Iyenger, Sudha; Sao, Satya; Jain, Bharat

doi:10.9734/ibrr/2013/4616

Cited by 14 publications

(17 citation statements)

References 36 publications

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“…9 Rhesus genotype is usually used for paternity testing in patients with Hemolytic Disease of New Born (HDN) and for predicting HDN through Rhesus genotype examination on a father if the mother has anti D. The most common father's genotypes provide a 0%, 50%, or 100% chance for the child to have a D Rhesus positive antigen. 11 However, this research did not aim to discuss the correlation between the diagnosis and the genotypes of the patients undergoing transfusion reactions.…”

Section: Resultsmentioning

confidence: 99%

“…Similarly, a research conducted by Zoysa NS 10 shows that the Rhesus positive is more prevalent in Asian populations than in Europe. 11 Besides, a research conducted by Akre 8 reveals that in sickle cell anemia patients, 62.8% of those patients receiving blood transfusions were affected by Rhesus and Kell antigens. Alloantibodies widely found in those patients were anti-E, anti-C and anti-Kell.…”

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confidence: 99%

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Analysis of Rhesus and Kell Genotype in Patients With Transfusion Reaction

Sukmawaty¹,

Muhiddin²,

Arif³

2018

Indonesian J. Clin. Pathol. Med. Lab.

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Transfusi darah dapat memberikan reaksi imunologis. Yang paling sering adalah reaksi transfusi terkait pecahnya sel darah(hemolitik) akibat tidak terdapatnya antibodi. Anti serum (Ab) yang disarankan saat ini untuk mendeteksi keberadaan antigen sel darahmerah yaitu ABO, Rhesus dan Kell. Penelitian ini bertujuan untuk mengetahui genotipe pasien Rhesus dan Kell dengan reaksi transfusi,menggunakan metode potong lintang di 35 subjek yang mengalami reaksi transfusi pada masa waktu antara bulan Juni–Agustus 2015di RS. Dr. Wahidin Sudirohusodo Makassar. Semua sampel diperiksakan antigen Rhesus dan Kell menggunakan sampel darah pasienyang ada di Bank Darah RS. Dr. Wahidin Sudirohusodo. Subjek penelitian rerata berumur 49,91 tahun dan sebagian besar berjeniskelamin perempuan (71,43%). Golongan darah yang paling banyak mengalami reaksi transfusi adalah golongan darah O (54,29%).Semua sampel adalah Rhesus positif (100%). Antigen D (100%), C (62,86%), c (40%), E (57,14%) dan e (91,43%). Antigen Kell diperolehK (8,57%) dan k (91,43%). Dari semua sampel sebagian besar antigen yang didapatkan adalah antigen D dan e, serta k.

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Section: Resultsmentioning

confidence: 99%

mentioning

confidence: 99%

Analysis of Rhesus and Kell Genotype in Patients With Transfusion Reaction

Sukmawaty¹,

Muhiddin²,

Arif³

2018

Indonesian J. Clin. Pathol. Med. Lab.

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“…Neonates having O-B incompatibility have been reported to develop hyperbilirubinemia within 24 h of life, more frequently than O-A incompatibility 23 ; however, the present study did not find such difference. In the Rh system, there are five major antigens of clinical importance: D, C, E, c, and e. In a study from central India, 24 the distribution of five major Rh antigens found was as follows: D-91.6%, C-84%, E-25.3%, c-58.3%, and e-78.5%. There are 18 possible phenotypic combinations; nine belong to Rh D positive, commonest being DCCee (41%), while the other nine belong to Rh D negative, commonest being dccee (5.6%).…”

Section: Discussionmentioning

confidence: 97%

Etiology and clinical profile of neonates with pathological unconjugated hyperbilirubinemia with special reference to Rhesus (Rh) D, C, and E incompatibilities: A tertiary care center experience

Singh

Kumar

et al. 2016

Clinical Epidemiology and Global Health

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“…Rh c antigen is comparatively common in India with frequency ranging from 52 to 62 % of Indian population [12][13][14][15][16], meaning thereby that finding Rh c antigen negative blood units is not an easy task. Resolution of such incompatibility issues and finding of implicated antigen negative blood units is time consuming, and jeopardizes transfusions in case of emergencies.…”

Section: Discussionmentioning

confidence: 99%