Incidence of sight-threatening retinopathy in patients with type 2 diabetes in the Liverpool Diabetic Eye Study: a cohort study

Younis, Naveed; Broadbent, Deborah; Vora, Jiten; Harding, Simon

doi:10.1016/s0140-6736(03)12267-2

Cited by 258 publications

(248 citation statements)

References 30 publications

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“…Around 79% of individuals invited for diabetic eye screening in England took up the offer of screening in 2010/2011 [4]. Patients who do not attend for screening have poorer HbA 1c and blood pressure control [7] and have been diagnosed with diabetes for longer [7,8], all of which are risk factors for developing retinopathy [8][9][10][11][12][13][14][15]. These observations suggest that patients who do not attend for eye screening might be at increased risk of diabetic eye disease.…”

Section: Introductionmentioning

confidence: 99%

Non-attendance at diabetic eye screening and risk of sight-threatening diabetic retinopathy: a population-based cohort study

Forster

Forbes

Dodhia³

et al. 2013

Diabetologia

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Aims/hypothesis This study evaluated whether repeated nonattendance for diabetic eye screening is associated with the risk of sight-threatening diabetic retinopathy (STDR). Methods This was a cohort study of 6,556 residents with diabetes who were invited for screening between 2008 and 2011 in a population-based eye screening programme in inner London and who attended for their first-ever screen in 2008. The proportion of participants with STDR was evaluated in relation to the number of years in which screening was missed.Results The proportion of participants who did not attend screening decreased between 2009 and 2011 (annual reduction 1.6% [95% CI 0.9%, 2.3%]). The adjusted relative odds of STDR for 210 participants who did not attend two consecutive years of screening were 3.76 (95% CI 2.14, 6.61; p<0.001), compared with participants who were screened annually. In 605 participants with mild non-proliferative retinopathy at the first screen, the adjusted relative odds of developing proliferative or moderate to severe nonproliferative retinopathy were 5.72 (95% CI 7.43, 22.83; p=0.013) for 53 participants who missed two screens. Conclusions/interpretation Patients who do not attend diabetic eye screening are at increased risk of developing STDR. Tracing of non-attenders with evidence of established retinopathy should be an important fail-safe procedure.

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Section: Introductionmentioning

confidence: 99%

Non-attendance at diabetic eye screening and risk of sight-threatening diabetic retinopathy: a population-based cohort study

Forster

Forbes

Dodhia³

et al. 2013

Diabetologia

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“…21,23 For the current study, we categorized DR severity as no DR (Early Treatment of Diabetic Retinopathy Study level 10-15), mild non-proliferative DR (NPDR; level 20), moderate NPDR (level [31][32][33][34][35][36][37][38][39][40][41][42][43], severe NPDR (level 53-60) and proliferative DR (PDR; level 61-80) using the eye with the most severe grading. The severity of DME was classified using the American Academy of Ophthalmology scale 25 as no, mild, moderate and severe DME.…”

Section: Assessment Of Dr and Dmementioning

confidence: 99%

Diet soft drink is associated with increased odds of proliferative diabetic retinopathy

Fenwick

Gan

Sabanayagam

et al. 2018

Clinical Exper Ophthalmology

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“…An ophthalmologist examined patients for the presence of diabetic eye disease and graded according to criteria used in the Liverpool Diabetes Eye Study. 16 Slit lamp examination with 78 or 90 D was performed after pupil dilatation using tropicamide 1% ophthalmic solution or phenylephrine 10% eye drops. If treatable abnormalities were detected, patients were offered further intervention when possible.…”

Section: Setting Queen Elizabeth Central Hospital (Qech) Inmentioning

confidence: 99%

A Survey of the Management, Control, and Complications of Diabetes Mellitus in Patients Attending a Diabetes Clinic in Blantyre, Malawi, an Area of High HIV Prevalence

Cohen¹,

Allain²,

Glover³

et al. 2010

The American Society of Tropical Medicine and Hygiene

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Abstract. The aim of this study was to describe the current status of diabetes care in an urban diabetes clinic in Malawi and the prevalence of human immunodeficiency virus (HIV) in this population, investigating possible associations between HIV and diabetes. A systematic prospective survey of patients attending the diabetes clinic at a teaching hospital in Blantyre, Malawi was conducted. Six hundred twenty patients were assessed. Seventy-four percent had glycosylated hemoglobin (HbA1C) > 7.5%. Systolic blood pressure was > 140 mm Hg in 52% of patients. Hypertension was more common in patients with raised creatinine ( P < 0.003), retinopathy ( P = 0.01), and stroke ( P < 0.0002). Microvascular complication rates were high, specifically nephropathy (34.7%), retinopathy (34.7%), and neuropathy (46.4%). HIV seroprevalence was 13.7%. HIV-positive subjects had a lower body mass index (BMI) and lower fasting blood sugar, and they were more likely to have albuminuria (48.0% versus 33.3%; P < 0.05). Control of glycemia and hypertension were poor, and microvascular complications were common. Nephropathy in diabetic patients may be affected by HIV status.

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Incidence of sight-threatening retinopathy in patients with type 2 diabetes in the Liverpool Diabetic Eye Study: a cohort study

Cited by 258 publications

References 30 publications

Non-attendance at diabetic eye screening and risk of sight-threatening diabetic retinopathy: a population-based cohort study

Non-attendance at diabetic eye screening and risk of sight-threatening diabetic retinopathy: a population-based cohort study

Diet soft drink is associated with increased odds of proliferative diabetic retinopathy

A Survey of the Management, Control, and Complications of Diabetes Mellitus in Patients Attending a Diabetes Clinic in Blantyre, Malawi, an Area of High HIV Prevalence

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