Incidence of stroke in Shibata, Japan: 1976-1978.

Background and Purpose: Temporal trends in stroke incidence in Denmark have not been previously reported. The Copenhagen City Heart Study is a prospective study based on a randomly selected sample of an urban population of, initially, 19,698 participants followed since 1976. Over a period of 12 years, we studied three important aspects of stroke incidence in 848 identified cases: temporal trends, dependence on age and sex, and comparison of responders and nonresponders.Methods: The participants were invited to two health examinations at 5-year intervals. The participants who attended at least one of the two examinations are termed responders and those who attended none nonresponders. The cases of first-ever stroke were collected from responders, the National Patient Register, and the National Register of Deaths and were verified by study of hospital records and death certificates.Results: For responders aged 35-64 years and ^65 years, there were no significant changes in the weighted rates in four consecutive 3-year periods. There was a tendency toward decreasing rates among younger women, but not in older women or men. The age-and sex-adjusted rates per 1,000 (based on the Danish population in 1982) in responders in the entire 12-year follow-up period were 1.61 in women, 2.67 in men, and 2.14 in both sexes combined. Stroke incidence rates increased exponentially with age in both sexes, with rates in men generally twice those in women, even in the ^75 years of age group. Age-adjusted rates were higher in nonresponders than in responders. For women, this ratio was 1.7; for men, 1.1.Conclusions: The stroke incidence in Copenhagen is relatively high and has shown no decreasing tendency over the period 1976-1988. {Stroke 1992^3^8-32)

Section: Downloaded Fromsupporting

confidence: 70%

Section: Downloaded Frommentioning

confidence: 74%

Stroke incidence in Copenhagen, 1976-1988.

Lindenstrøm

Boysen

Nyboe

et al. 1992

“…[7][8][9][10][11][12][13][14][15][16] Previous studies in China, Hong Kong, Taiwan, and Japan generally found that 23% to 52.2% of strokes were hemorrhagic, [3][4][5][6][21][22][23][24][25] in contrast to only 9% to 18% in whites. [7][8][9][10][11][12][13][14][15][16] In the present study, 29.6% of stroke cases overall in 2000 were hemorrhagic in Chinese populations, which supported the above idea that an ethnic difference existed between Eastern and Western populations.…”

Section: Stroke Subtypes In Chinese Populations Compared With Westernmentioning

confidence: 99%

Proportion of Different Subtypes of Stroke in China

Zhang

Yang

Hong

et al. 2003

315

193

Background and Purpose-The goal of this article is to clarify the proportion of stroke subtypes in China, where stoke is the most common cause of death. Methods-A total of 16 031 first-ever strokes in subjects Ն25 years of age were identified in 1991 to 2000 from 17 Chinese populations through a community-based cardiovascular disease surveillance program in the China Multicenter Collaborative Study of Cardiovascular Epidemiology. World Health Organization diagnosis criteria were used for classification of stroke subtypes. Results-CT scan rate of stroke cases reached a satisfactorily high level only after 1996 in the study populations. In 8268 first-ever stroke events from 10 populations with CT scan rate Ͼ75% in 1996 to 2000, 1.8% were subarachnoid hemorrhage, 27.5% were intracerebral hemorrhage, 62.4% were cerebral infarction, and 8.3% were undetermined stroke. The proportion of intracerebral hemorrhage varied from 17.1% to 39.4% and that for cerebral infarction varied from 45.5% to 75.9% from population to population. The ratio of ischemic to hemorrhagic stroke ranged from 1.1 to 3.9 and averaged 2.0). The 28-day fatality rate was 33.3% for subarachnoid hemorrhage, 49.4% for intracerebral hemorrhage, 16.9% for cerebral infarction, and 64.6% for undetermined stroke. Conclusions-In our study, ischemic stroke was more frequent and its proportion was higher than hemorrhagic stroke in Chinese populations. Although hemorrhagic stroke was more frequent in Chinese than in Western populations, the variation in the proportion of stroke subtypes among Chinese populations could be as large as or larger than that between

“…2,3 The natural history and pathogenesis of perihematomal edema in human spontaneous intracerebral hemorrhage (SICH) are just beginning to be understood, particularly in the hyperacute setting. Carefully documenting the genesis and evolution of edema is a necessary first step in understanding the pathogenesis of edema and whether it might be altered by treatment strategies aimed at reducing edema-related morbidity and mortality.…”

mentioning

confidence: 99%

“…This study is a secondary analysis of data prospectively collected during a population-based study of hematoma growth after hyperacute SICH, whose original results have been previously reported. 4 Patients in this study systematically underwent baseline CT scanning within 3 hours of clinical ICH onset, with repeated studies at 1 and 20 hours after baseline CT. We sought (1) to summarize edema volumes in both absolute and relative terms (see below) and (2) to explore the presence of associations between edema volume and relevant clinical and radiological variables.…”

mentioning

confidence: 99%

Natural History of Perihematomal Edema in Patients With Hyperacute Spontaneous Intracerebral Hemorrhage

Gebel

Jauch

Brott³

et al. 2002

223

144

Background and Purpose-The natural history of perihematomal edema in human hyperacute spontaneous intracerebral hemorrhage (ICH) has not been well described. Methods-This study was a secondary analysis of a previously reported prospective, population-based study of hematoma growth in 142 patients with spontaneous ICH. Patients were first imaged within 3 hours of onset, then 1 and 20 hours later. We excluded patients with anticoagulant use (nϭ7), underlying aneurysm/vascular malformation (nϭ9), trauma (nϭ1), incomplete data (nϭ20), infratentorial ICH (nϭ17), and no consent (nϭ2), leaving an overall study population of 86 patients. From this overall group we further excluded patients with intraventricular extension (nϭ38), subsequent surgery (nϭ5), or death (nϭ2) before 20-hour postbaseline CT. This second, "restricted" analysis group of 41 patients was relatively devoid of clinical or radiological variables likely to confound edema measurement. Absolute and relative edema volumes (edema volume divided by hematoma volume) were descriptively summarized. Correlations between baseline edema volumes and relevant clinical and radiological variables were then performed. Results-Overall, median absolute edema volume increased from 6.93 to 14.4 cm 3 during the first 24 hours after ICH, and median relative edema volume increased from 0.47 to 0.81. In the restricted group, median absolute edema volume was 7.4 cm 3 at baseline and 11.0 cm 3 at 24 hours after ICH, and median relative edema volume increased from 0.55 to 0.81. Baseline relative edema volume was significantly negatively correlated with subsequent change in relative edema volume from baseline to 20-hour CT (rϭ0.57, Pϭ0.0002) but was not significantly correlated with other clinical and radiological variables, including hematoma volume or change in hematoma volume. Conclusions-Perihematomal edema volume increases by approximately 75% during the first 24 hours after hyperacute spontaneous ICH. Patients with the least amounts of baseline relative edema volume were most likely to develop significant additional amounts of edema during the first 24 hours after spontaneous ICH.