Incidental Gallbladder Carcinoma Diagnosed During or After Laparoscopic Cholecystectomy

Zhang, Weijie; Xu, Guifang; Zou, Xiaoping; Wang, Weibing; Yu, Jie-Xiang; Wang, Guozhong; Chen, Lu

doi:10.1007/s00268-009-0218-9

Cited by 63 publications

(57 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The mean age of incidental carcinoma detection in our study was 57.8 years, however, in other studies from various parts of world including Saudi, Japan, China and Italy the mean age of presentation is higher than 65 years [7,11,13,14]. The youngest male patient affected in our study group was 32 years and on re-exploration surgery he had liver involvement.…”

Section: Discussioncontrasting

confidence: 62%

Incidental Detection of Carcinoma Gall Bladder in Laparoscopic Cholecystectomy Specimens: A Thirteen Year Study of 23 Cases and Literature Review

Gulwani

Gupta

Kaur

2015

Indian J Surg Oncol

View full text Add to dashboard Cite

Carcinoma of gall bladder is the most common malignancy of the biliary tract worldwide and is usually associated with poor prognosis. In this era of laparoscopic cholecystectomy, there has been increase in detection of early stage incidental gall bladder carcinoma in cholecystectomy specimens. A retrospective study was carried out in tertiary care hospital in central India. A total of 2990 patients underwent laparoscopic cholecystectomy during the year 2001-2013. Hospital records and histopathology reports of these patients were studied in detail. Twenty three cases of gall bladder carcinoma were detected incidentally accounting for an incidence of 0.76 %. It was more common in females with an M: F ratio of 1:1.9. Mean age of presentation was 57.8 years. Gall stones were present in 22 cases and one patient presented with features of acute cholecystitis. Three patients had associated xanthogranulomatous inflammation and 10 had associated intestinal metaplasia. It is not uncommon to encounter incidental malignancies of gall bladder in laparoscopic cholecystectomy specimens sent to histopathology for presumably benign disease. Histopathology reports must include comments on extent of infiltration, perineural invasion, tumor differentiation and nodal involvement for oncologist information and subsequent management of patients.

show abstract

Section: Discussioncontrasting

confidence: 62%

Incidental Detection of Carcinoma Gall Bladder in Laparoscopic Cholecystectomy Specimens: A Thirteen Year Study of 23 Cases and Literature Review

Gulwani

Gupta

Kaur

2015

Indian J Surg Oncol

View full text Add to dashboard Cite

show abstract

“…The similar study conducted by Khan et al (10) and Thaml Selvi et al (9) reported the gallbladder carcinoma 2.2% and 1.2% respectively. The incidence of gallbladder carcinoma diagnosed during or after a cholecystectomy has been reported to be between 0.19% and 3.3% (11). Despite advance in diagnostic and surgical modalities , gallbladder carcinoma is still characterized by late diagnosis and poor prognosis except when incidentally diagnosed at an early stage after cholecystectomy for choleliothiasis.…”

Section: Discussionmentioning

confidence: 99%

Histopathological Study of Gallbladder Lesions in East Singhbhum, Jharkhand

Murmu¹,

Topno²,

Baitha³

2017

IOSR JDMS

View full text Add to dashboard Cite

“…All the six cases of the incidentally detected gallbladder carcinoma in this series were females and their average age was 53 years. A review of the literature showed that 0.19% to 3.3% of the patients who underwent cholecystectomies for presumed benign diseases were found to have carcinomas of the gallbladder [1][2][3][4][5] Tantia et al, in a study of LC cases from the Indian metropolis of Kolkata, reported an incidence of 0.59% of IGBC [2]. The present study which was based in New Delhi, India showed an incidence of 0.96% of IGBC among LC cases over a five and a half year period.…”

Section: Discussionmentioning

confidence: 99%

Incidental Gall Bladder Carcinoma in Laparoscopic Cholecystectomy: A Report of 6 Cases and a Review of the Literature

Jetley¹,

Sabina²,

H³

et al. 2013

JCDR

View full text Add to dashboard Cite

Background: Gall bladder carcinoma accounts for 98% of all the gall bladder malignancies and it is the sixth most common malignancy of the gastrointestinal tract worldwide. The incidence of incidental gall bladder carcinoma which is diagnosed during or after a laparoscopic cholecystectomy is reported to be around 0.19-3.3% in the literature.Aim: This study was aimed at detecting the incidence of gall bladder carcinomas which were diagnosed incidentally during or after laparoscopic cholecystectomies which were done for gall stone disease and cholecystitis. Materials and Methods:We analyzed the medical records of patients with symptomatic gallstone disease and acute or chronic cholecystitis, who underwent laparoscopic cholecystectomies at the Hakeem Abdul Hameed Centenary Hospital during the period from January 2007 to June 2012.Results: A total of 622 laparoscopic cholecystectomies were performed at our institute during the study period of five and a half years. In 6 (0.96%) cases, incidental carcinomas of the gallbladder were discovered. Conclusion:A laparoscopic cholecystectomy which is performed for benign gall bladder disease rarely results in a diagnosis of unexpected gallbladder cancer. The microscopic examination of the specimens, with special attention to the depth of invasion, range of the mucosal spread and the lymphovascular involvement, is critical in diagnosing the incidental malignancies as well as for the subsequent management of the cases.

show abstract

Incidental Gallbladder Carcinoma Diagnosed During or After Laparoscopic Cholecystectomy

Cited by 63 publications

References 31 publications

Incidental Detection of Carcinoma Gall Bladder in Laparoscopic Cholecystectomy Specimens: A Thirteen Year Study of 23 Cases and Literature Review

Incidental Detection of Carcinoma Gall Bladder in Laparoscopic Cholecystectomy Specimens: A Thirteen Year Study of 23 Cases and Literature Review

Histopathological Study of Gallbladder Lesions in East Singhbhum, Jharkhand

Incidental Gall Bladder Carcinoma in Laparoscopic Cholecystectomy: A Report of 6 Cases and a Review of the Literature

Contact Info

Product

Resources

About