Encoded within catchment hydrology are complex interactions among catchments' climatic and physical (e.g., soil, geology, and topography) attributes. Large spatial-temporal variabilities of these attributes, and diverse interactions among them, give rise to diverse catchment-scale streamflow generation mechanisms, in catchments around the world (Blöschl et al., 2014). This diversity complicates the understanding of the dominant streamflow generation mechanisms in a given catchment (Wu et al., 2021), which are central to obtaining the "right streamflow predictions for the right reasons" (Kirchner, 2006). As qualitatively showed by Dunne (1978) and Dooge (1986), there could be a generalizable catchment-scale scientific framework that explains and synthesizes the baffling diversity of streamflow generation mechanisms. Such a framework could allow the transfer and regionalization of the mechanisms (McDonnell et al., 2007;Wagener et al., 2007), essentially required to predict streamflow responses in poorly gauged regions (McDonnell & Woods, 2004). There is, however, little in the way of a scientific framework to quantitatively explain why variations in dominant streamflow generation mechanisms occur between catchments (Li et al., 2014). This quantitative framework, to be generalizable, should be developed based on globally available catchment data and should explain how interactions among catchment attributes influence the way a catchment transforms (or filters) climatic variability into streamflow variability (Troch, Berne, et al., 2013). This study takes a small step toward developing and testing (the application of) one such generalizable quantitative framework.Several studies showed the efficiency of a small set of interactive indices to describe a catchment's hydrologic behavior and predict the signatures of the catchment water balance, within the context of large-sample hydrology (LSH). LSH uses (globally) available datasets of catchment physical and climatic attributes and