This paper presents an integrated framework for capacity and operations planning in Spanish sheltered employment centers (SECs). Employment provides socio-economic opportunities for people with disability. Well functioning SECs that provide opportunities for people with and without disability to work alongside each other are an important component of Spain’s current labor market. To be economically sustainable, SECs need to satisfy their clients expectations in terms of price, flexibility and performance, whilst taking into account and strengthening the diverse skills and abilities of their workforce like specific learning and forgetting processes. The SEC studied herein, a non-for-profit organization whose mission is to create employment for people with disabilities its workforce is deployed directly on clients’ premises. Efficient management across this multi-site environment, whilst supporting the diverse employment needs of its staff, is of paramount importance. This paper contributes an integrated framework to support SEC capacity and operations planning, which prioritizes the explicit training needs of workers with disability at all levels (strategic, tactical, and operational) as a lever for achieving the organization’s goals.