Incomplete Kawasaki Disease Manifesting as Transient Heart Failure in a Previously Healthy Adolescent

Yamauchi, Atsushi; Nakagawa, Naoki; Kawamura, Y.; Hasebe, Naoyuki

doi:10.2169/internalmedicine.51.7413

Cited by 3 publications

(3 citation statements)

References 13 publications

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“…Another 18 cases were documented in other case reports. [18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33] Among the 136 reported cases, including ours, the oldest patient was 17 years old, 27,32 suggesting that KD can affect patients of any age because adult-onset KD in patients from 18 to 68 years of age has also been previously identified. KD in adolescents is more likely to affect male patients.…”

Section: Discussionmentioning

confidence: 99%

Clinical characteristics of Kawasaki disease in adolescents

et al. 2021

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Objective Studies focusing on Kawasaki disease (KD) in adolescents are lacking in Southwest China. We systematically summarized the clinical characteristics of KD in adolescents to improve pediatricians’ recognition of this condition. Methods The clinical data of patients with adolescent-onset KD in our center were retrospectively analyzed. The patients were divided into Group A (n = 7), whose first hospitalization was at our hospital, and Group B (n = 10), who were transferred from their local hospital or community health center. Results Seventeen patients with adolescent-onset KD were identified (constituent ratio of 0.8%). Seven patients had an intermittent fever for >10 days. The incidence of incomplete KD was 52.9%. These patients had a high incidence of other atypical clinical manifestations. Fifteen patients were initially misdiagnosed with other infectious diseases. Although the incidence of typical KD was higher in Group B, the overall misdiagnosis rate at the initial stages was higher and the average fever duration on arrival and before IVIG administration were much longer in Group B than A. Conclusions KD in adolescents was frequently misdiagnosed, which might be associated with its atypical, diverse clinical features and pediatricians’ poor recognition. Pediatricians must be aware of the possibility of KD in adolescents.

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Section: Discussionmentioning

confidence: 99%

Clinical characteristics of Kawasaki disease in adolescents

et al. 2021

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“…One case report described a 16-year-old female patient with heart failure, prolonged febrile illness, bilateral conjunctivitis, transaminitis, and elevated CRP. 3 Several aneurysms were found on coronary artery angiography and persisted 1 year later. 3 Another case described a 31year-old woman with transient heart failure, including reduced LVEF and pulmonary edema in the acute phase of KD.…”

Section: Discussionmentioning

confidence: 99%

“…3 Several aneurysms were found on coronary artery angiography and persisted 1 year later. 3 Another case described a 31year-old woman with transient heart failure, including reduced LVEF and pulmonary edema in the acute phase of KD. 4 Distributive and cardiogenic shock are involved in KDSS.…”

Section: Discussionmentioning

confidence: 99%

A Case of Adult-Onset Kawasaki Disease Shock Syndrome Complicated by Coronary Aneurysms

et al. 2019

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We present a case of adult-onset Kawasaki disease shock syndrome complicated by coronary aneurysms, in which profound hypotension and reduced left ventricular ejection fraction were treated successfully with intravenous immunoglobulin. The diagnosis of Kawasaki disease shock syndrome should be considered in cases of rapidly developing shock, particularly in young adults with an infectious prodrome, in whom it may be under-recognized. We advocate for early identification to minimize delays in treatment with intravenous immunoglobulin, which reverses left ventricular dysfunction and decreases risk of longterm sequelae such as coronary artery aneurysms.

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Abdominal lymphadenopathy in an adolescent with Kawasaki disease: a major sign?

Bulkool

Carvalho

Grippa

et al. 2016

International Journal of Adolescent Medicine and Health

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In adolescence, Kawasaki disease (KD) may present with varied clinical pictures, and the classic clinical criteria are often insufficient to establish the diagnosis. This report presents a clinical case of KD in an adolescent and a brief review of the relevant literature, based on a PubMed search using the terms "adolescence" and "KD". A 13-year-old girl presented with fever, rash, hepatomegaly, and ultrasonographic evidence of abdominal lymphadenopathy. On week 2 after onset of symptoms, the patient developed desquamation of the extremities and thrombocytosis. Echocardiography was normal during the acute illness and remained unchanged at 2-year follow-up. Clinicians should be aware that, in adolescents, KD poses a diagnostic challenge and rarely corresponds to the classic presentation. On retrospective analysis, we believe that abdominal lymphadenopathy should have been recognized as a substitute manifestation of the classic symptom of cervical lymphadenopathy to establish the diagnosis of this fearsome systemic vasculitis syndrome.

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Incomplete Kawasaki Disease Manifesting as Transient Heart Failure in a Previously Healthy Adolescent

Cited by 3 publications

References 13 publications

Clinical characteristics of Kawasaki disease in adolescents

Clinical characteristics of Kawasaki disease in adolescents

A Case of Adult-Onset Kawasaki Disease Shock Syndrome Complicated by Coronary Aneurysms

Abdominal lymphadenopathy in an adolescent with Kawasaki disease: a major sign?

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