Incorporation routes of elements into human hair; implications for hair analysis used for monitoring

Bos, A.J.J.; Stap, C. C. A. H. van der; Valković, V.; Vis, R.D.; Verheul, H.

doi:10.1016/0048-9697(85)90015-4

Cited by 54 publications

(17 citation statements)

References 15 publications

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“…First, an unacceptably high proportion of hair-root samples did not have a sheath, or the portion of the hair-root in which endogenous lead reportedly is deposited is [6]. Second, the time to conduct the scan (1,000 sec per scan and three scans totals 50 min per sample) is prohibitively long.…”

Section: Discussionmentioning

confidence: 99%

“…X-ray fluorescence spectrometry can determine the lead content in short segments of hair [5]. Because lead has been reported to be deposited into the sheath of the hair-root [6] and that this portion of the hair extends into the skin, a hair-root sample may be less prone to external contamination, and thus may be useful in screening for elevated lead levels.…”

Section: Introductionmentioning

confidence: 99%

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Hair-root lead to screen for lead toxicity

Campbell

Toribara

2001

J. Trace Elem. Exp. Med.

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The objective of ths study was o determine the validity of a hair‐root lead level for the screening of elevated blood lead levels. Children who required a screening blood lead level were eligible for enrollment. After consent, a venipuncture blood sample was obtained from each child and, concurrently, three to five hair samples were plucked from the scalp. All telogen hairs and samples without a hair‐root sheath were discarded. Two samples were assayed using X‐ray fluorescence spectrometry: one was from a child with a blood lead level of 1 μg/dL and the second was from a child with a blood lead level of 54 μg/dL. A total of 148 hair‐root samples were obtained. Only 59 (40%) had a hair‐root sheath. The average elemental count, which is a measure of the amount of lead at the position of the hair‐root being measured, was 313 for a child with a blood lead level of 1 μg/dL and 266 for a child with a blood lead level of 54 μg/dL. These counts are very low, essentially the same, and very close to the background counts. The findings of this study do not support the use of hair‐root samples for the screening of elevated blood lead levels. J. Trace Elem. Exp. Med. 14:69–72, 2001. © 2001 Wiley‐Liss, Inc.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Hair-root lead to screen for lead toxicity

Campbell

Toribara

2001

J. Trace Elem. Exp. Med.

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“…Analytical studies, however, have established that lead concentration in hair increases along its length and that this pattern indicates external exposure and its duration (e.g., Bos et al, 1985). It is clear, therefore, that the major source of hair lead is exogenous.…”

Section: Lead Biomarkersmentioning

confidence: 96%

A Comment on “The Adventures of Lead Commander: An Environmental Education Program to Prevent Lead Poisoning in Young Children”

Tsuji¹,

Nieboer

2001

The Journal of Environmental Education

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“…Lead is incorporated into human hair and hair roots (Bos et al 1985;) and has been explored as a possibly noninvasive approach for estimating lead body burden (Gerhardsson et al 1995b;Wilhelm et al 1989). The method is subject to error from contamination of the surface with environmental lead and contaminants in artificial hair treatments (i.e., dyeing, bleaching, permanents) and is a relatively poor predictor of PbB, particularly at low concentrations (<12 μg/dL) (Campbell and Toribara 2001;Drasch et al 1997;Esteban et al 1999).…”

Section: Health Effectsmentioning

confidence: 99%