Increase in sexually transmitted infections in a cohort of outpatient HIV-positive men who have sex with men in the Parisian region

Farfour, Éric; Dimi, Svetlane; Majerholc, C.; Fourn, Erwan; Sené, Thomas; Chaida, M.B.; Vasse, Marc; Zucman, David

doi:10.1016/j.medmal.2017.06.004

Cited by 7 publications

(4 citation statements)

References 11 publications

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“…Moreover, 46.9% patients were known to be HIV positive, 10.8% positive for syphilis and 5.7% positive for both HIV and syphilis. Coinfection with HIV is frequently reported in other case series (Farfour et al, 2017;Heras et al, 2011;Martin-Iguacel et al, 2010;McCoy et al, 2009;Montoya-Ferrer et al, 2011). The high rate of coinfections is related to a trivialization of the risk induced by the advances in HIV treatments.…”

Section: Discussionmentioning

confidence: 97%

“…These data may be related to the specificity of the proctology center, which is considered as an expert center for anorectal STI in this population. Moreover, this study is focused on the population located in Paris, where STIs are more frequently reported than in other areas (Farfour et al, 2017;France, 2015).…”

Section: Discussionmentioning

confidence: 99%

“…The main clinical and socio-demographic characteristics are shown in Table 1. Median time to the onset of clinical symptoms (anal or rectal pain, tenesmus, feeling false need, purulent rectal discharge) before consultation was seven days (Dang et al, 2009;Cohen, 2006;Price et al, 2013;Cabello Ubeda et al, 2016;Wind et al, 2017;Bonnet et al, 2013;Dudareva-Vizule et al, 2014;Benn et al, 2007;France, 2015;Farfour et al, 2017;de Vrieze et al, 2013;Kent et al, 2005;Hook et al, 2008;Dukers-Muijrers et al, 2015a;Mabey and Peeling, 2002;Van der Bij et al, 2006;Pallawela et al, 2014;Ward et al, 2007), with 44.2% of the patients having consulted a general practitioner after seven days. Previous history of STI and/or anorectal infection was found for 39.1% of the patients.…”

Section: General Characteristicsmentioning

confidence: 99%

See 2 more Smart Citations

Clinical diagnostic and therapeutic aspects of 221 consecutive anorectal Chlamydia trachomatis and Neisseria gonorrhoeae sexually transmitted infections among men who have sex with men

Hascoet¹,

Dahoun²,

Cohen³

et al. 2018

International Journal of Infectious Diseases

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: General Characteristicsmentioning

confidence: 99%

See 1 more Smart Citation

Clinical diagnostic and therapeutic aspects of 221 consecutive anorectal Chlamydia trachomatis and Neisseria gonorrhoeae sexually transmitted infections among men who have sex with men

Hascoet¹,

Dahoun²,

Cohen³

et al. 2018

International Journal of Infectious Diseases

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“…Furthermore, STI trends in HIV-positive MSM could have be influenced by the “undetectable = untransmittable” (U = U) campaigns. In high-income countries such as France, the burden of STIs is particularly high in MSM and HIV-infected patients [ 3 , 4 ]. In France, some STIs such as lymphogranuloma venereum (LGV) are diagnosed almost exclusively in MSM, who represented 95% of all cases reported in 2016.…”

Section: Introductionmentioning

confidence: 99%

Trends in asymptomatic STI among HIV-positive MSM and lessons for systematic screening

Farfour

Dimi²,

Chassany

et al. 2021

PLoS ONE

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The burden of STIs is particularly high in HIV-infected MSM patients. A recent increase in STIs prevalence has been noticed in the US and western European countries. We aim to assess trends in asymptomatic STIs following the publication of recommendations for STIs screening, i.e. Chlamydia (CT) and gonorrhea (NG). Seventeen centers located in the Paris area participated in the study. All asymptomatic HIV-infected MSM patients attending a follow up consultation were proposed to participated in the study. Asymptomatic patients were included over 2 periods: period 1 from April to December 2015 and period 2 from September to December 2017. Etiologic diagnosis of STIs including hepatitis B, C, syphilis, was performed using a serological test, including a non-treponemal titer with a confirmatory treponemal assay for syphilis. CT and NG were screened using a nucleic acid amplification test (NAATs) on 3 anatomical sites, i.e. urine, rectal and pharyngeal. Overall, 781 patients were included: 490 and 291 in periods 1 and 2 respectively. Asymptomatic CT, NG, and syphilis were diagnosed in 7.5%, 4.8% and, 4.2% respectively. The rate of patients having a multisite asymptomatic infection was 10.2% and 21.1% for CT and NG respectively. The most frequently involved anatomical sites for CT and NG asymptomatic infections were anorectal (66.1% and 55.2% respectively) and pharyngeal (47.4% and 60.5% respectively). CT and NG asymptomatic infection increased by 1.3- and 2-fold respectively between the two periods while syphilis decreased by 3 folds. Our results encourage to reconsider multisite screening for CT and NG in asymptomatic HIV positive MSM as the yield of screening urinary samples only might be low. Despite the more systematic STI screening of asymptomatic HIV positive MSM the prevalence of STI is increasing in MSM in France. Therefore, this strategy has not led to alter CT and NG transmission. The decrease of syphilis might involve self-medication by doxycycline, and the intensification of syphilis screening.

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Estudio retrospectivo acerca de la evolución y el desarrollo de resistencias antimicrobianas en casos diagnosticados de gonorrea en un hospital de nivel terciario en Portugal durante 10 años

Queirós

Borges‐Costa

Lito

et al. 2020

Actas Dermo-Sifiliográficas

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Increase in sexually transmitted infections in a cohort of outpatient HIV-positive men who have sex with men in the Parisian region

Cited by 7 publications

References 11 publications

Clinical diagnostic and therapeutic aspects of 221 consecutive anorectal Chlamydia trachomatis and Neisseria gonorrhoeae sexually transmitted infections among men who have sex with men

Clinical diagnostic and therapeutic aspects of 221 consecutive anorectal Chlamydia trachomatis and Neisseria gonorrhoeae sexually transmitted infections among men who have sex with men

Trends in asymptomatic STI among HIV-positive MSM and lessons for systematic screening

Estudio retrospectivo acerca de la evolución y el desarrollo de resistencias antimicrobianas en casos diagnosticados de gonorrea en un hospital de nivel terciario en Portugal durante 10 años

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