Increased exercise level and plasma lipoprotein concentrations: A one-year, randomized, controlled study in sedentary, middle-aged men

Wood, Peter D.; Haskell, William L.; Blair, Steven N.; Williams, Paul T.; Krauss, Ronald M.; Lindgren, Frank T.; Albers, John J.; Ho, Ping; Farquhar, John W.

doi:10.1016/0026-0495(83)90152-x

Cited by 335 publications

(152 citation statements)

References 29 publications

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“…Sixteen RCTs [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] were identified that had compared weight loss in groups assigned physical activity alone with that in groups assigned no intervention. A summary of the findings of these RCTs is included in Table 1.…”

Section: Physical Activity Alonementioning

confidence: 99%

“…Of the 16 RCTs, 11 found statistically significant improvements in weight loss with exercise compared with controls. 2,3,[5][6][7][9][10][11]13,16,17 The magnitude of the differences in weight outcomes between groups in these studies was small. Weight loss in the exercise group ranged from 0.1 kg to 5.2 kg, with most studies showing weight loss of only 1-3 kg.…”

Section: Physical Activity Alonementioning

confidence: 99%

“…Fogelholm and Kukkonen-Harjula 57 reviewed all research reports published between 1980 and early 2000 that had data on physical activity and weight gain or regain with follow-up of more than 1 year. Prospective observational studies (16), nonrandomized studies (19), and RCTs (11) were included. The results from observational studies, but not clinical trials, suggested that exercise leads to successful weight-loss maintenance.…”

Section: The Role Of Physical Activity In Maintaining Weight Lossmentioning

confidence: 99%

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The role of physical activity in producing and maintaining weight loss

2007

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SummaryThe majority of randomized, controlled trials (RCTs) show only modest weight loss with exercise intervention alone, and slight increases in weight loss when exercise intervention is added to dietary restriction. In most RCTs, the energy deficit produced by the prescribed exercise is far smaller than that usually produced by dietary restriction. In prospective studies that prescribed high levels of exercise, enrolled individuals achieved substantially greater weight losscomparable to that obtained after similar energy deficits were produced by caloric restriction. High levels of exercise might, however, be difficult for overweight or obese adults to achieve and sustain. RCTs examining exercise and its effect on weight-loss maintenance demonstrated mixed results; however, weight maintenance interventions were usually of limited duration and long-term adherence to exercise was problematic. Epidemiologic, cross-sectional, and prospective correlation studies suggest an essential role for physical activity in weight-loss maintenance, and post hoc analysis of prospective trials shows a clear dose-response relationship between physical activity and weight maintenance. This article reviews the role of physical activity in producing and maintaining weight loss. We focus on prospective, RCTs lasting at least 4 months; however, other prospective trials, meta-analyses and large systematic reviews are included. Limitations in the current body of literature are discussed.

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Section: Physical Activity Alonementioning

confidence: 99%

Section: Physical Activity Alonementioning

confidence: 99%

Section: The Role Of Physical Activity In Maintaining Weight Lossmentioning

confidence: 99%

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The role of physical activity in producing and maintaining weight loss

2007

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“…Eighty-one sedentary men, 30-55 years old, were assigned at random to either a supervised running group of 48 persons or to a sedentary control group of 33 persons [8,11]. Recruitment, selection criteria, and experimental design are described elsewhere [8].…”

Section: Subjects and Laboratory Measurementsmentioning

confidence: 99%

“…Long-distance runners have higher HDL-cholesterol concentrations than sedentary men [7,8]. Marneimi et al [9,10] have speculated that an increase in the runners' LCAT activity may produce their high HDL-cholesterol levels.…”

Section: Introductionmentioning

confidence: 99%

Associations of lecithin: cholesterol acyltransferase (LCAT) mass concentrations with exercise, weight loss, and plasma lipoprotein subfraction concentrations in men

et al. 1990

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The relationships between plasma 1ecithin:cholesterol acyltransferase (LCAT) mass concentrations and lipids, apolipoprotein, and lipoprotein subfraction concentrations were studied in men assigned at random to a one-year exercise program (n = 48) and to a sedentary control condition (n = 31). Exercise training did not significantly affect mean concentrations of LCAT-mass. Moreover changes in LCAT within the exercise group were unrelated to distance run and weight loss. The baseline data and the one-year change data showed consistent positive correlations between LCAT concentrations and total cholesterol, low density lipoprotein cholesterol, very low density lipoprotein cholesterol, and apolipoprotein B concentrations, and consistently weak correlations between LCAT concentrations and high density lipoprotein (HDL)-cholesterol, HDL 2 , and apolipoprotein A-I concentrations. The strong correlation between LCAT and total cholesterol may account for LCAT's relationships with lipoprotein subfractions, apolipoprotein B and other lipoprotein cholesterol concentrations.

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Effects of exercise, dietary cholesterol, and dietary fat on blood lipids

Johnson

Greenland

1990

Archives of Internal Medicine

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Increased exercise level and plasma lipoprotein concentrations: A one-year, randomized, controlled study in sedentary, middle-aged men

Cited by 335 publications

References 29 publications

The role of physical activity in producing and maintaining weight loss

The role of physical activity in producing and maintaining weight loss

Associations of lecithin: cholesterol acyltransferase (LCAT) mass concentrations with exercise, weight loss, and plasma lipoprotein subfraction concentrations in men

Effects of exercise, dietary cholesterol, and dietary fat on blood lipids

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