Increased mean platelet volume associated with extent of slow coronary flow

The relationship between neutrophil gelatinase-associated lipocalin levels and the slow coronary flow phenomenon

“…SCF is deemed to be present if the TFCs are 2 SD above the normal mean values. As such, in our study, we defined SCF to be at least 42 for the LAD, at least 31 for the LCX, and at least 27 for the RCA [10].…”

Prognostic value of platelet indices after acute myocardial infarction treated with primary percutaneous coronary intervention

“…In the present study, PVI are also raised in a small (10.2%) subset of patients with past history of MI compared to those with the first episode of an acute coronary event; in the literature there is also evidence of protracted circulation of larger platelets after acute MI [6,7,13]. The presence of larger platelet size in patients with history of the coronary artery disease may be interpreted as a consequence of platelet consumption at the site of coronary lesion and subsequent stimulation of the bone marrow [2]. Platelets produced under conditions of stimulated thrombocytopoiesis, called "stress" platelets by Tong at al.…”

“…Large platelets are considered metabolically and enzymatically more reactive than smaller ones [1]. Increased mean platelet volume (MPV) is associated with extent of slow coronary flow [2]. MPV has been reported as increased in unstable angina pectoris and myocardial infarction (MI) [3].…”

Red cell distribution width: A novel infl ammatory marker in clinical practice

“…Previous studies have demonstrated that elevated levels of infl ammatory molecules are markers of atherosclerotic disease activity and also indicate an increased risk for the progression of atherosclerosis. So, there is a signifi cant relationship between the endothelial dysfunction, and inflammatory parameters and cardiovascular risk factors such as hypertension, diabetes mellitus, smoking and hypercholesterolemia [5]. Because these factors may affect the levels of RDW, compared to patient groups, control groups should be similar in features according to risk factors and in terms of the number of the individuals.…”