Increased Oxacillin Resistance in Thigh Pyomyositis in Diabetic Patients

Abstract

Thigh abscesses due to pyomyositis are uncommon. To guide empiric antibiotic therapy in diabetics we determined the rate of such infections due to oxacillin-resistant Staphylococcus aureus and Gram-negative organism infections, and whether the occurrence of oxacillin-resistant pathogens increased during the study period. We retrospectively reviewed 39 adult patients with diabetes mellitus treated for a deep thigh abscess. There were 29 men and 10 women; their mean age was 45 years. Comorbidities were present in 15 patients. S. aureus was the most common pathogen, present in 82% (32/39) of our patients. Gram-negative organisms were cultured in 14%

Pyomyositis; Frequency and Its Common Bacteria With Their Antibiotic Sensitivity Among Children With Highly Suspected Clinical Features

“…Classically, it is an infection of the tropics, occurring in previously active and healthy young men. 9 Pyomyositis in temperate countries is often regarded as an infection that occurs in hosts who are immune compromised or otherwise debilitated.…”

Primary pyomyositis: an unusual presentation in an older patient with no recognised risk factors

“…Timing of presentation and the clinical stage affects the imaging findings but early MRI is invaluable even in the absence of a collection 12. Early identification of the pathogen is crucial to guide in antibiotic choice as there is an increasing incidence of methicillin-resistant S aureus being isolated from infected individuals13 14 only a small minority of which may have favourable outcomes 15…”

The Socioeconomic Impact of Musculoskeletal Infections

“…Most of them are superficial and are readily treated with local care and oral antibiotics. However, they may affect deeper structures including fascia and muscle 16 . Charalambous et al 86 reported on 142 consecutive hospital admissions to treat acute soft-tissue infections of the extremities between 1996 and 2001; half of the infections were cellulitis and a substantial proportion (fortythree) were abscesses.…”

“…Soft-tissue infections such as cellulitis, abscesses, and pyomyositis from community-acquired methicillinresistant Staphylococcus aureus occur with increasing frequency in athletes, especially in those engaged in team sports [14][15][16] . Health-care-acquired methicillin-resistant Staphylococcus aureus generally affects acutely and chronically ill patients with central lines, indwelling catheters, and internal fixation devices, causing septic arthritis, osteomyelitis, and bacteremia 17 .…”