Increased size‐sorting performance in gravitational SPLITT by using a pinched sample inlet design

Abstract

Increased size-sorting performance in gravitational SPLITT by using a pinched sample inlet design Split-flow thin fractionation is a continuous, flow-assisted separation technique for sorting macromolecules and particulate matter on a preparative scale. On reducing the thickness of the sample inlet conduit of a gravitational split-flow thin fractionation channel, size-sorting performance is found to increase since particles that are continuously fed into the channel can be more rapidly compressed toward the upper wall of the channel. Experiments are carried out by measuring the number percentage of particles eluted at each outlet as a function of different thickness values of the sample inlet conduit. The effects that the total thickness of the gravitational split-flow thin fractionation channel and the sample feed concentration have on the size-fractionation performance are examined with the goal of determining the best pinched sample inlet, gravitational split-flow thin fractionation channel design.

Size fractionation of marine sediments by pinched inlet gravitational split‐flow thin fractionation and the study of size dependent PCDD/Fs concentrations from different bay areas

“…A PI-GSF channel was built in house as described in previous reports [13,14]. Four different channel dimensions were used in this study to achieve particle separation at each different cut-off diameter.…”

“…The theoretical relationship between cut-off diameter and flow rate conditions can be found in the literature [9,13,14]. In every fractionation step (corresponding to each different cut-off diameter), a two stage fractionation procedure was used: a rough cut at a relatively high feed rate followed by a precision cut at a low feed rate by re-injecting the collected particle suspension.…”

“…Pinched inlet gravitational split-flow thin fractionation (PI-GSF) utilizes a modified type of GSF channel characterized by reduced thickness of the sample inlet conduit, as shown in Figure 1, and has been shown to give improved separation efficiency [13,14]. Since particles leaving the inlet splitter of a PI-SPLITT channel can be quickly transported and efficiently pushed against the upper wall of the GSF channel by the carrier stream, the number of particles departing from an ideal trajectory during the initial transportation toward the upper channel wall can be decreased to some degree.…”

Pinched Inlet Split Flow Thin Fractionation for Continuous Particle Fractionation: Application to Marine Sediments for Size-Dependent Analysis of PCDD/Fs and Metals

“…In this study, it is demonstrated that GSF can be effectively utilized for the continuous separation of sea sediments and that the resulting fractions of a narrow diameter range can be analyzed for the study of the size-dependent levels of PCDD/Fs and heavy metals. To enhance SPLITT fractionation efficiency, our work adopts the pinched inlet SPLITT channel design (shown in Figure ) that was developed in a previous work by reducing the thickness of the sample inlet conduit of GSF channel. By applying the pinched inlet design to the GSF channel, particles leaving the inlet splitter can be quickly transported and efficiently pushed against the upper wall of the GSF channel by the carrier stream so that the number of particles leaving from an ideal trajectory expected during sample injection is decreased to some degree.…”

Effect of Sample-loading on Fractionation Efficiency (FE) in a Large Scale Splitter-less Gravitational SPLITT Fractionation (GSF)

“…1,8,9 Conventionally, GSF is carried out in a thin ribbon-like channel equipped with two splitters between the top and bottom inlets and outlets of the channel, respectively. 10 A schematic view of a GSF channel is shown in Figure 1(a).…”