The adequate method of antibiotic choice is reported using the laser°uorescence analysis of blood plasma with the laboratory diagnostic device \Spectrolux-MB". The method is based on the ability of micro-organisms and products of their vital functions (metabolism) to°uoresce under laser radiation. The method of°uorescence analysis has great prospects in urgent surgery and other medicine brunches due to its high information content, low cost (compared to other methods of express-diagnostics) and high speed of information acquisition.