Increasing sucrose concentrations promote phenylpropanoid biosynthesis in grapevine cell cultures

Regulation of stilbene biosynthesis in plants

“…Two studies report on the effect of sucrose added to the culture medium on stilbene production in grapevine cell suspension cultures. While Larronde et al (1998) reported on only a slight modulating effect of sucrose application on stilbene production, Ferri et al (2011) demonstrated that increasing sucrose concentrations promote stilbene production in the cell suspensions. Tavares et al (2013) reported that stilbene biosynthesis in photosynthetic and nonphotosynthetic tissues of V. vinifera is affected by sulfur deficiency.…”

“…Flavonoid production is known to be induced in response to various environmental stresses and nutritional factors, e.g., microbial and virus infections, high-light stress, UV irradiation, unfavorable temperatures, drought, or increased sucrose concentrations (Miranda et al 2007;Gutha et al 2010;Ferri et al 2011;Zhang et al 2012;Nakabayashi et al 2014;Degu et al 2016). These factors modulate different regulatory proteins that control flavonoid biosynthesis by regulating transcription of the genes encoding flavonoid biosynthesis enzymes or transcription factors.…”

The role of sugar signaling in plant defense responses against fungal pathogens

“…This phenomenon was initially described as a characteristic of plants prone to low-sugar diseases (Horsfall and Diamond 1957). In recent literature it is termed ''high-sugar resistance'' and includes the induction of several plant defense mechanisms (Ferri et al 2011). Basing on the latest published research results, an attempt will be made to clarify the varied involvement of sugars in the immune system of plants.…”

“…It has also been reported that sucrose and hexoses can play an important role in resistance to fungal pathogens through stimulation of phenylpropanoid metabolism (Forlani 2010;Morkunas et al 2011;Gibertia et al 2012). Phenylpropanoid pathway allows plants to produce various secondary metabolites in defense response to infection (Ferri et al 2009(Ferri et al , 2011. These include flavonoids (isoflavonoids in particular), which can play the role of phytoalexins in plants from the family Fabaceae (Andersen and Markham 2006;Bednarek and Osbourn 2009;Naoumkina et al 2010).…”

Accumulation of flavanols and expression of leucoanthocyanidin reductase induced by postharvest UV-C irradiation in grape berry

“…This may be one of the reasons for flavanol polyphenol accumulation by suitable UV-C irradiation. Moreover, UV-C irradiation increased the activity of a key enzyme (phenylalanine ammonialyase, PAL) in the initial stages of the phenylpropanoid pathway and induced gene expression of chalcone synthase (Ferri et al, 2011), flavanone 3-hydroxylaase, and dihydroflavonol 4-reductase . Therefore, the increased LAR activity may be related to increased substrate concentration resulting from the specific expression of structural genes in the phenylpropanoid and flavonoid pathway induced by UV-C irradiation.…”