Independent association of vitamin D and insulin resistance in obstructive sleep apnea

Fan, Zeqin; Cao, Bing; Hong, Liu; Feng, Lijie; Li, Qianjun; Zhang, Yanhong; Li, Taoping

doi:10.1016/j.ando.2019.09.004

Cited by 12 publications

(9 citation statements)

References 28 publications

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“…In this study, the ndings about for HbA1c were similar to the literature. HOMO-IR is a parameter used as marker of insulin resistance and values above 2.7 are seen as insulin resistance [41]. In this study, individuals with metabolic syndrome had HOMO-IR values of 6.13±3.71 above the reference interval, as expected, and higher than the individuals in the healthy control group (p<0.05) (Table 3).…”

Section: Discussionsupporting

confidence: 74%

The Relationship Between Coronavirus Anxiety Level and Emotional Eating in Individuals with Metabolic Syndrome: A Comparative Study

Değirmenci

Uğurlu

Alemdar

2021

Preprint

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BackgroundThe aim was to determine the coronavirus anxiety levels and emotional eating status of cases with diagnosis of MetS according to diagnostic criteria published by the International Diabetic Federation (IDF) in 2005 and healthy individuals with similar BMI to MetS subjects. MethodsThis study was completed with the descriptive, cross-sectional, case-controlled and relational screening model. The full sampling method was used in the study. The study was completed with 105 individuals with metabolic syndrome attending the diet clinic and 109 healthy individuals without MetS diagnosis also attending the diet clinic. Collection of data used anthropometric measurements and biochemical findings, blood pressure and a survey form, the Coronavirus Anxiety Scale (CAS) and Emotional Eating Scale (EES). ResultsCoronavirus anxiety scale scores of individuals with metabolic syndrome were found to be statistically significantly higher than the scores of the healthy control group (p <0.05). The difference between the metabolic syndrome group and the healthy control group for emotional eating scale scores was not significant (p <0.05)When groups are compared, apart from HDL, blood pressure and all other biochemical parameters were higher in metabolic syndrome subjects (p<0.05). However, when the correlation between coronavirus anxiety scale and emotional eating scale points is investigated in metabolic syndrome and healthy individuals, there was no correlation between the two scales (p>0.05).ConclusionIndividuals with metabolic syndrome had higher coronavirus anxiety levels than healthy individuals; however, there was no difference between metabolic syndrome and healthy subjects in terms of emotional eating behavior.Level of evidenceIII, case–control analytic study.

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Section: Discussionsupporting

confidence: 74%

The Relationship Between Coronavirus Anxiety Level and Emotional Eating in Individuals with Metabolic Syndrome: A Comparative Study

Değirmenci

Uğurlu

Alemdar

2021

Preprint

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“…Patients with OSA and insulin resistance (IR) had lower levels of serum 25(OH)D3 compared with those without IR, further regression analysis found a negative association of 25(OH)D3 levels with IR. 26,27 One possible explanation for the above findings maybe that vitamin D deficiency enhanced IR by promoting inflammation. 28 Additionally, vitamin D may contribute to the increased risks of infections and inflammations which are involved in the upper and lower airway.…”

Section: Discussionmentioning

confidence: 99%

<p>The Relationship of Serum 25-Hydroxyvitamin-D Level with Severity of Obstructive Sleep Apnea in Patients with Type 2 Diabetes Mellitus</p>

Zheng²,

Dong

et al. 2020

DMSO

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To explore the association of serum vitamin-D levels with the severity of obstructive sleep apnea (OSA) in patients with type 2 diabetes mellitus (T2DM). Methods: A cross-sectional study of 136 patients with T2DM who underwent overnight polysomnography (PSG) tests and serum 25-hydroxyvitamin-D3 (25(OH)D3) level detections was conducted. Multivariable linear regression and logistic regression analyses were performed to determine the associations of serum 25(OH)D3 levels with apnea-hypopnea index (AHI) and obstructive sleep apnea (OSA).Results: The prevalence rates of OSA were 84.4% for male and 65.2% for female patients, respectively (p = 0.011). With increasing severities of OSA categories (none, mild, moderate and severe), patients were more likely to be male and obese, but there was no significant difference in serum 25(OH)D3 level ((mean ± standard deviation) 21.8 ± 8.8, 27.7 ± 14.6, 24.2 ± 9.8 and 26.8 ± 6.2 ng/mL, respectively, p=0.086). Serum 25(OH)D3 level was not significantly correlated with AHI (log-transformed), with the correlation coefficient of 0.133 (p=0.124). With adjustment for potential confounding factors, multivariable linear regression and logistic regression analyses showed that serum 25(OH)D3 level was not significantly associated with either AHI (log-transformed) or the risk of OSA, with the standardized regression coefficient (95% confidence interval (CI)) of 0.098 (−0.004-0.014, p=0.252) and the adjusted odds ratio (95% CI) of 1.055 (0.991-1.124, p=0.095), respectively. Conclusion: Serum 25(OH)D3 level was not significantly associated with either AHI or the risk of OSA in patients with T2DM.

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“…Zegin Fan et al found that IR in the severe OSAS group was significantly higher than in the control group. Vitamin D values are negatively correlated with AHI and IR [16]. We did not measure IR, because the study was retrospective and this was not our aim.…”

Section: Discussionmentioning

confidence: 99%

Vitamin D in obstructive sleep apnea syndrome follow up and treatment: A study of 482 cases

et al. 2021

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Independent association of vitamin D and insulin resistance in obstructive sleep apnea

Cited by 12 publications

References 28 publications

The Relationship Between Coronavirus Anxiety Level and Emotional Eating in Individuals with Metabolic Syndrome: A Comparative Study

The Relationship Between Coronavirus Anxiety Level and Emotional Eating in Individuals with Metabolic Syndrome: A Comparative Study

<p>The Relationship of Serum 25-Hydroxyvitamin-D Level with Severity of Obstructive Sleep Apnea in Patients with Type 2 Diabetes Mellitus</p>

Vitamin D in obstructive sleep apnea syndrome follow up and treatment: A study of 482 cases

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