InDiaMed: A Comprehensive Database of Indian Medicinal plants for Diabetes

Abstract

According to International Diabetes Federation (IDF), India has 62.4 million people with diabetes and by 2030 it is predicted that the number will rise to 100 million. Studies claim that there are around 410 experimentally proven Indian medicinal plants which have anti-diabetic activity, of which the mechanism of action of 109 plants has been elucidated or reported. So, the need of the hour is to explore the claims of Indian medicinal flora and open up the facets of many Indian plants which are being examined for their beneficial role in diabetes. So, we created a database (InDiaMed) of Indian medicinal plants that captures their role in anti-diabetic activity. InDiaMed's features include chemical, pharmacological, biochemical and geographical information of the medicinal plant, scientifically relevant information of the plant, and the coherent research done on it in the field of diabetes. The database also includes the list of poly-herbal formulations which are used for treatment of diabetes in India.Availabilityhttp://www.indiamed.info

Focus on Proteomics and Bioinformatics in Translational Research and Plant Research of Obesity and Diabetes

“…Plants, DIAB can be given as examples to such databases [65][66][67][68]. These databases which can be accessed alphabetically using genus name serve to provide a platform for diabetes research.…”

“…All databases are based primarily on data collection, design and their features and utility. Data are collected from various literature sources such as Pubmed, ScienceDirect, Mary Ann Liebert, BlackWell Synergy, Ingentaconnect, Scirus, Bentham Publishers, Wiley journals, Journals of phyto-medicine, Journal of Ethanopharmacology, Biomed Central, Springerlink and also from folklore medicinal usage for all databases [65][66][67][68].…”

Closing the Gap Between Therapeutic Use and Mode of Action in Remedial Herbs

“…This is schematically illustrated in Figure 1 . A number of publicly available well annotated databases on medicinal plants in use in different regions of the planet exist already (Chen, 2011; James et al, 2013; Ntie-Kang et al, 2013; Tota et al, 2013; Pathania et al, 2015; Mohanraj et al, 2018). Once data connecting the different aspects of ethnopharmacological relevance are known, the circle is closed and mechanistic hypotheses emerge naturally.…”

Association of JAZF1 and TSPAN8/LGR5 variants in relation to type 2 diabetes mellitus in a Saudi population

“…An estimated number of 285 million people are currently diabetic worldwide, and this is expected to increase up to 438 million by the year 2030. [ 2 – 4 ]. Worldwide, Saudi Arabia ranks seventh in T2DM prevalence and the incidence of this disease has doubled over the last two decades in the kingdom [ 1 ].…”