Indications and Outcomes of Phototherapeutic Keratectomy in the Developing World

Abstract

PTK is an efficacious treatment modality for symptomatic relief and visual gain in cases with superficial corneal involvement and bullous keratopathy.

Comparative Evaluation of Phototherapeutic Keratectomy and Amniotic Membrane Transplantation for Management of Symptomatic Chronic Bullous Keratopathy

“…[9][10][11][12][13][14][15][16][17][18] Several studies have shown encouraging results after PTK in eyes with bullous keratopathy. [4][5][6][7][8] The proposed mechanism of action of PTK in bullous keratopathy is by ablation of the superficial epithelial nerve plexus, ablationrelated reduction of stromal ''osmotic load,'' thereby increasing endothelial efficacy in its dehydrating function and creation of a smooth anterior surface. 5 In a retrospective study on 103 eyes that underwent PTK for bullous keratopathy at our centre, 4 a significant decrease (P , 0.0001) in the number of patients with severe symptoms was noted after treatment.…”

“…The symptoms were graded on a fixed response scale (Table 1). 4 Patients with a category score of .2 were considered for PTK or AMT, and eligible patients were randomized into 2 groups using randomization charts.…”

“…1 However, some of these eyes carry a poor visual prognosis, and their ocular discomfort may be treated with other modalities like a Gunderson flap, 2 anterior stromal puncture, 3 excimer laser phototherapeutic keratectomy (PTK), [4][5][6][7][8] or amniotic membrane transplantation (AMT). [9][10][11][12][13][14][15][16][17][18] There have been several reports on the outcome of PTK and AMT in patients with bullous keratopathy, and both modalities have been found to be effective.…”

Update on phototherapeutic keratectomy

“…A recent report from a tertiary eye care center in India confirmed PTK as an efficacious treatment modality for symptomatic relief and visual gain in cases with superficial corneal involvement and bullous keratopathy [16 ]. This is a retrospective study of 203 consecutive eyes of 191 patients who underwent PTK in the Rajendra Prasad Centre for Ophthalmic sciences in New Delhi with 6-month follow-up.…”

Salzmannsche noduläre Hornhautdegeneration

“…Die Laserchirurgie als primärer abtragender Eingriff [13,41] dürfte aber nur für kleine Knötchen geeignet sein. Massive Aufwachsungen sollten primär mechanisch entfernt werden, wie es auch über-wiegend Praxis ist.…”