Indocyanine Green Angiography of Choroidal Neovascular Membranes

Hayashi, Kazuhiko; Laey, J. J. De

doi:10.1159/000309489

Cited by 75 publications

(42 citation statements)

References 7 publications

(8 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In comparison, the vascular fluorescence seen with ICG was less intense. According to these features, in accordance with the other authors' opinions, we saw that FA could image well-defined CNV better than ICGV [5,7].…”

Section: Discussionsupporting

confidence: 89%

Evaluation of Choroidal Neovascularization in Age-Related Macular Degeneration with Fluorescein and Indocyanine Green Videoangiography

Atmaca¹,

Batıoğlu²,

Atmaca³

1996

Ophthalmologica

View full text Add to dashboard Cite

This study is performed to evaluate the fluorescein and indocyanine green (ICG) characteristics of choroidal neovascularization (CNV) in age-related macular degeneration (ARMD). 200 eyes of 101 patients were examined with digital ICG videoangiography (ICGV). 190 of the 200 eyes had macular lesions of ARMD, and CNVs were detected in 84 (44.2%) of them. Angiographies confirmed the presence of well-defined CNV in 40 (47.6%) eyes and occult CNV in 44 (52.4%) eyes. On ICG-videoangiographic examination, 6 (13.6%) of the 44 eyes with occult CNV had vascularized pigment epithelial detachment, 27 (61.4%) had a vascularized retinal pigment epithelium. Laser photocoagulation had been performed on the remaining 11 (25%) eyes. The results of this study suggest that ICGV is a valuable technique in the diagnosis and evaluation of occult CNVs and may be suggested as an additional diagnostic tool in cases with choroidal neovascular membranes.

show abstract

Section: Discussionsupporting

confidence: 89%

Evaluation of Choroidal Neovascularization in Age-Related Macular Degeneration with Fluorescein and Indocyanine Green Videoangiography

Atmaca¹,

Batıoğlu²,

Atmaca³

1996

Ophthalmologica

View full text Add to dashboard Cite

show abstract

“…We agree with Hayashi and De Laey [2] and Yannuzzi et al [9] that in some cases of AMD the CNV grows inside or at the margins of the watershed zones; in our study the per centage o f correspondence between the CNV and wa tershed zones was 71%: 75% in CCNV; 70% in occult CNV ( fig. 3).…”

Section: Relationship Between Cnv and Watershed Zonessupporting

confidence: 92%

“…These data support the hypothesis of a relationship between areas of presumed choroidal ischemia and evolution of AMD compli cated with CNV The role of the choroid in the physiopathology of agerelated macular degeneration (AMD) is still controversial. After the first observations of Hayashi and De Laey [1,2] concerning a relation between choroidal neovascularization (CNV) and watershed zones, or areas of choroidal atrophy, Pauleikhoff ct al. [3] underlined the importance of a fluorangiographic delay of choroidal filling in the evolution of the nonexudative form of the disease.…”

mentioning

confidence: 99%

Choroidal Filling in Age-Related Macular Degeneration: Indocyanine Green Angiographic Findings

Giovannini

Mariotti²,

Ripa³

et al. 1994

Ophthalmologica

View full text Add to dashboard Cite

We studied the choroidal filling patterns in 145 patients with age-related macular degeneration (AMD), looking for a correlation with choroidal neovascularization (CNV). We found a correspondence in 71% of cases between the site of the CNV and watershed areas and in 59% of cases between the CNV and areas of ‘delayed choroidal filling’ These data support the hypothesis of a relationship between areas of presumed choroidal ischemia and evolution of AMD complicated with CNV.

show abstract

“…Since the subfoveal choriocapillary circulation is not always visible on FA because the macular xanthophyll pigment absorbs the exciting blue light used in FA, SLO-ICGv may provide greater information with regard to the choriocapillary circulation than FA. In addition, the choriocapillary circulation over areas of thin subretinal/subRPE hemorrhage may be obscured on FA, but be visible on SLO-ICGv because of the lack of absorption of the exciting or emitted SLO-ICGv infrared light by hemoglobin [14][15][16][17][18]. We used two diagnostic tools stereoscopic, FA and SLO-ICGv, to assess the choroidal circulation [19][20][21][22][23][24][25] in ARMD-eyes with SFCNVM both before and after submacular surgery.…”

Section: Discussionmentioning

confidence: 99%

Choroidal hypoperfusion after surgical excision of subfoveal neovascular membranes in age-related macular degeneration

et al. 1997

View full text Add to dashboard Cite

Purpose. To study the choroidal circulation after surgical excision of subfoveal choroidal neovascular membranes (SFCNVM) in age-related macular degeneration (ARMD). Methods. Twelve eyes of eleven patients with ARMD that underwent surgical excision of SFCNVMs were evaluated with stereoscopic color fundus photography, stereoscopic fluorescein angiography (FA) and scanning laser ophthalmoscope-indocyanine green videoangiography (SLOICGv). The patients were followed for a mean of 7.9 months (range 2 to 14 months). Results. Preoperatively, all eyes had angiographic evidence of a SFCNVM, with SLO-ICGv showing the presence of a choriocapillary blush. Postoperatively, stereoscopic color fundus photographs documented that the bed of the surgical excision was characterized by an absence of visible retinal pigment epithelial (RPE) pigmentation in all eyes. Stereoscopic FA of the excision bed revealed choriocapillary hypofluorescence with visible dye perfusion in the underlying medium and large choroidal vessels in all eyes. SLO-ICGv of the excision bed disclosed the presence of perfused medium and large choroidal vessels, but a marked choroidal hypofluorescence with loss of the choriocapillary and small choroidal vascular filling within the excision bed in eleven of the twelve eyes. Conclusion. Our results indicate that both choriocapillary and small choroidal vascular filling is frequently abnormal or absent in the bed of surgically excised subfoveal neovascular membranes in ARMD. This finding, which may represent either pathologic or iatrogenic choriocapillary and small choroidal vascular atrophy or occlusion with preservation of perfusion in the underlying medium and large choroidal vessels, may influence structural and visual recovery after submacular surgery for ARMD, despite RPE transplantation or regeneration.

show abstract

Indocyanine Green Angiography of Choroidal Neovascular Membranes

Cited by 75 publications

References 7 publications

Evaluation of Choroidal Neovascularization in Age-Related Macular Degeneration with Fluorescein and Indocyanine Green Videoangiography

Evaluation of Choroidal Neovascularization in Age-Related Macular Degeneration with Fluorescein and Indocyanine Green Videoangiography

Choroidal Filling in Age-Related Macular Degeneration: Indocyanine Green Angiographic Findings

Choroidal hypoperfusion after surgical excision of subfoveal neovascular membranes in age-related macular degeneration

Contact Info

Product

Resources

About