Indocyanine green conjugated phototheranostic nanoparticle for photodiagnosis and photodynamic therapy

Shinoda, Kenta; Suganami, Akiko; Moriya, Yasumitsu; Yamashita, Masamichi; Tanaka, Tsutomu; Suzuki, Akane; Suito, Hiroshi; Akutsu, Yasunori; Saito, Kengo; Shinozaki, Yoko; Isojima, Kazuoki; Nakamura, Naohito; Miyauchi, Yasushi; Shirasawa, Hiroshi; Matsubara, Hisahiro; Okamoto, Yoshiharu; Nakayama, Toshinori; Tsutsumi, Yutaka

doi:10.1016/j.pdpdt.2022.103041

Cited by 5 publications

(2 citation statements)

References 67 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…CQD [185] Tannic acid 84.5 CQD [186] Ananas 23.3 GQD [188] Pyrene 80 Cl-CQD [189] Citric acid, urea, NaCl 88 CQD [190] Tomato 63.8 CQD [191] Pomelo 56 T-CQD [192] Thumbai 89 CQD [193] Taurine 82.5 S-CQD [194] Turmeric and ammonium persulfate 79.5 CD [195] Carica papaya leaves 86 CD [196] Beta vulgaris 94.5 CQD [197] Citrus clementina peel 81.4 TCD [198] Green tea 75 rcCQD [199] Red cabbage 61 N-CD [200] Black soya 93.8 N,S-CD [201] Pomelo and sulfamic acid 82…”

Section: Title Source Materials Scavenging Activity (%)mentioning

confidence: 99%

Lights and Dots toward Therapy—Carbon-Based Quantum Dots as New Agents for Photodynamic Therapy

et al. 2023

View full text Add to dashboard Cite

The large number of deaths induced by carcinoma and infections indicates that the need for new, better, targeted therapy is higher than ever. Apart from classical treatments and medication, photodynamic therapy (PDT) is one of the possible approaches to cure these clinical conditions. This strategy offers several advantages, such as lower toxicity, selective treatment, faster recovery time, avoidance of systemic toxic effects, and others. Unfortunately, there is a small number of agents that are approved for usage in clinical PDT. Novel, efficient, biocompatible PDT agents are, thus, highly desired. One of the most promising candidates is represented by the broad family of carbon-based quantum dots, such as graphene quantum dots (GQDs), carbon quantum dots (CQDs), carbon nanodots (CNDs), and carbonized polymer dots (CPDs). In this review paper, these new smart nanomaterials are discussed as potential PDT agents, detailing their toxicity in the dark, and when they are exposed to light, as well as their effects on carcinoma and bacterial cells. The photoinduced effects of carbon-based quantum dots on bacteria and viruses are particularly interesting, since dots usually generate several highly toxic reactive oxygen species under blue light. These species are acting as bombs on pathogen cells, causing various devastating and toxic effects on those targets.

show abstract

Section: Title Source Materials Scavenging Activity (%)mentioning

confidence: 99%

Lights and Dots toward Therapy—Carbon-Based Quantum Dots as New Agents for Photodynamic Therapy

et al. 2023

View full text Add to dashboard Cite

show abstract

“…[42,43] As a clinically approved photosensitizer, indocyanine green (ICG) has been extensively exploited for tumor eradication under near-infrared (NIR) light stimulation, thanks to its splendid ROS quantum yield. [44,45] And, the incorporation of ICG into nanocarriers has been proved to realize an effective tumor-specific drug delivery during cancer therapy. [46] To this end, the alliance of supramolecular fibrillation and NIR-triggered photosensitization is anticipated to realize an aggravated disruption of tumor cell membrane, resulting from a synergistic physiochemical effect from physical injury and lipid peroxidation.…”

Section: Introductionmentioning

confidence: 99%

Enzyme‐Activatable Polypeptide for Plasma Membrane Disruption and Antitumor Immunity Elicitation

Liu

Zhang

et al. 2023

Small

View full text Add to dashboard Cite

In addition, the principal components of plasma membrane bridge intracellular signals with extracellular messages (e.g., cytokines, hormones, and ligands), which exert profound influence on the regulation of cellular signaling networks. [3,4] Severe injuries in cytomembrane may cause acute pathologies and pose an instant threat to cell survival, owing to the vast change of intracellular landscape upon cytosolic leakage. [5,6] Specifically, the pervasive dyshomeostasis may give rise to deleterious proteolysis, calcium imbalance, and osmotic pressure, ultimately causing cell death. [7,8] Thus far, the disruption of cytomembrane integrity can be categorized into the following two approaches: chemical damage and physical disruption.

show abstract

Photodynamic therapy combined with immunotherapy: Recent advances and future research directions

Warszyńska,

Repetowski,

Dąbrowski

2023

Coordination Chemistry Reviews

View full text Add to dashboard Cite

Indocyanine green conjugated phototheranostic nanoparticle for photodiagnosis and photodynamic therapy

Cited by 5 publications

References 67 publications

Lights and Dots toward Therapy—Carbon-Based Quantum Dots as New Agents for Photodynamic Therapy

Lights and Dots toward Therapy—Carbon-Based Quantum Dots as New Agents for Photodynamic Therapy

Enzyme‐Activatable Polypeptide for Plasma Membrane Disruption and Antitumor Immunity Elicitation

Photodynamic therapy combined with immunotherapy: Recent advances and future research directions

Contact Info

Product

Resources

About