Indocyanine Green (ICG) and Colorectal Surgery: A Literature Review on Qualitative and Quantitative Methods of Usage

Simion, Laurentiu; Ionescu, Sinziana; Chitoran, Elena; Rotaru, Vlad; Cirimbei, Ciprian; Madge, Octavia-Luciana; Nicolescu, Alin Codrut; Tanase, Bogdan; Dicu-Andreescu, Irinel-Gabriel; Dinu, Denisa Mihaela; Luca, Dan Cristian; Stanculeanu, Dana Lucia; Gheorghe, Adelina Silvana; Zob, Daniela; Marincas, Marian

doi:10.3390/medicina59091530

Cited by 10 publications

(5 citation statements)

References 110 publications

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“…A delicate balance needs to be achieved, and in our opinion, a 1 cm thickness of the skin flap is optimal. Lastly, in order to minimize the risk of flap necrosis, techniques using Indocyanine green may be employed for assessing the perfusion of the flap used for breast reconstruction [47].…”

Section: Oncologic Follow-up and Results After Reconstructive Surgerymentioning

confidence: 99%

Breast Reconstruction following Mastectomy for Breast Cancer or Prophylactic Mastectomy: Therapeutic Options and Results

Simion,

Petrescu,

Chitoran

et al. 2024

Life

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(1) Importance of problem: Breast cancer accounted for 685,000 deaths globally in 2020, and half of all cases occur in women with no specific risk factor besides gender and age group. During the last four decades, we have seen a 40% reduction in age-standardized breast cancer mortality and have also witnessed a reduction in the medium age at diagnosis, which in turn means that the number of mastectomies performed for younger women increased, raising the need for adequate breast reconstructive surgery. Advances in oncological treatment have made it possible to limit the extent of what represents radical surgery for breast cancer, yet in the past decade, we have seen a marked trend toward mastectomies in breast-conserving surgery-eligible patients. Prophylactic mastectomies have also registered an upward trend. This trend together with new uses for breast reconstruction like chest feminization in transgender patients has increased the need for breast reconstruction surgery. (2) Purpose: The purpose of this study is to analyze the types of reconstructive procedures, their indications, their limitations, their functional results, and their safety profiles when used during the integrated treatment plan of the oncologic patient. (3) Methods: We conducted an extensive literature review of the main reconstructive techniques, especially the autologous procedures; summarized the findings; and presented a few cases from our own experience for exemplification of the usage of breast reconstruction in oncologic patients. (4) Conclusions: Breast reconstruction has become a necessary step in the treatment of most breast cancers, and many reconstructive techniques are now routinely practiced. Microsurgical techniques are considered the “gold standard”, but they are not accessible to all services, from a technical or financial point of view, so pediculated flaps remain the safe and reliable option, along with alloplastic procedures, to improve the quality of life of these patients.

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Section: Oncologic Follow-up and Results After Reconstructive Surgerymentioning

confidence: 99%

Breast Reconstruction following Mastectomy for Breast Cancer or Prophylactic Mastectomy: Therapeutic Options and Results

Simion,

Petrescu,

Chitoran

et al. 2024

Life

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“…Clinical and imaging follow-up were the only approaches. Laparoscopic approaches, the ICG-guided sampling of pelvic lymph nodes, and other types of modified surgical procedures, although described as possibilities in the literature, were not indicated for our patients due to the technical particularities of the cases [11][12][13].…”

Section: Methodsmentioning

confidence: 99%

Why Is Surgery Still Done after Concurrent Chemoradiotherapy in Locally Advanced Cervical Cancer in Romania?

Voinea,

Bordea,

Chitoran

et al. 2024

Cancers

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The incidence and mortality of cervical cancer are high in Romania compared to other European countries, particularly for locally advanced cervical cancer cases, which are predominant at the time of diagnosis. Widely accepted therapeutic guidelines indicate that the treatment for locally advanced cervical cancer consists of concurrent chemoradiotherapy (total dose 85–90 Gy at point A), with surgery not being necessary as it does not lead to improved survival and results in significant additional morbidity. In Romania, the treatment for locally advanced cervical cancer differs, involving lower-dose chemoradiotherapy (total dose 60–65 Gy at point A), followed by surgery, which, under these circumstances, ensures better local control. In this regard, we attempted to evaluate the role and necessity of surgery in Romania, considering that in our study, residual lesions were found in 55.84% of cases on resected specimens, especially in cases with unfavorable histology (adenocarcinoma and adenosquamous carcinoma). This type of surgery was associated with significant morbidity (28.22%) in our study. The recurrence rate was 24.21% for operated-on patients compared to 62% for non-operated-on patients receiving suboptimal concurrent chemotherapy alone. In conclusion, in Romania, surgery will continue to play a predominant role until radiotherapy achieves the desired effectiveness for local control.

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“…It is well established that the incidence of breast cancer rises with age, but there has been an observed 11% increase in new diagnoses among women under 45 years old recently [1]. This shift has led healthcare providers to focus on QoL by modified surgical procedures aimed at limiting side-effects [114][115][116], reconstructive surgery [117], and fertility preservation options for these women, given the long-term toxicity concerns associated with the necessary treatment. Approximately 10% of breast cancer cases are diagnosed in women under 40, indicating that many require onco-fertility care, often disrupting family planning upon diagnosis.…”

Section: Breast Cancermentioning

confidence: 99%

Navigating Fertility Preservation Options in Gynecological Cancers: A Comprehensive Review

Chitoran,

Rotaru,

Mitroiu

et al. 2024

Cancers

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(1) Background: Currently, an increasing number of women postpone pregnancy beyond the age of 35. Gynecological cancers affect a significant proportion of women of reproductive age, necessitating the development of fertility preservation methods to fulfill family planning. Consequently, providing treatment options that preserve fertility in women diagnosed with gynecological cancers has become a crucial component of care for survivors. (2) Methods: We conducted an extensive search of relevant scientific publications in PubMed and Embase databases and performed a narrative review, including high-quality peer-reviewed research on fertility after being treated for gynecologic cancers, reporting pregnancy rates, birth rates, and pregnancy outcomes in cancer survivors as well as therapeutic options which partially preserve fertility and methods for obtaining a pregnancy in survivors. (3) Discussion: The medicine practiced today is focused on both treating the neoplasm and preserving the quality of life of the patients, with fertility preservation being an important element of this quality. This leads to an improved quality of life, allowing these women to become mothers even in the seemingly adverse circumstances posed by such a pathology. However, although there are guidelines on female fertility preservation in the context of neoplasms, an analysis shows that physicians do not routinely consider it and do not discuss these options with their patients. (4) Conclusions: Advancements in medicine have led to a better understanding and management of gynecological neoplasms, resulting in increased survival rates. Once the battle against these neoplasms is won, the issue of preserving the quality of life for these women arises, with fertility preservation being an important aspect for women who have not yet fulfilled their family planning desires at the time of diagnosis. It is important for patients to be informed about the available options for fertility preservation and to be encouraged to make informed decisions in collaboration with their medical team. Standardized recommendations for onco-fertility into guidelines should be taken into consideration in the future.

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Indocyanine Green (ICG) and Colorectal Surgery: A Literature Review on Qualitative and Quantitative Methods of Usage

Cited by 10 publications

References 110 publications

Breast Reconstruction following Mastectomy for Breast Cancer or Prophylactic Mastectomy: Therapeutic Options and Results

Breast Reconstruction following Mastectomy for Breast Cancer or Prophylactic Mastectomy: Therapeutic Options and Results

Why Is Surgery Still Done after Concurrent Chemoradiotherapy in Locally Advanced Cervical Cancer in Romania?

Navigating Fertility Preservation Options in Gynecological Cancers: A Comprehensive Review

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