Indoor air quality during renovation actions: a case study

Hameed, A. A. Abdel; Yasser, I. H.; Khoder, Mamdouh I.

doi:10.1039/b402995j

Cited by 44 publications

(16 citation statements)

References 20 publications

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“…Distinct from Cryptococcus , however, Aspergillus can produce small asexual spores, called conidia, which are 2–3 μm in diameter. The dispersal of A. fumigatus produces conidia that are hydrophobic and can spread and sustain for a much longer time in the air, making it a highly virulent fungus [ 53 , 54 , 55 ]. In healthy individuals, epithelial cells in the airway and alveolar macrophages efficiently eliminate inhaled conidia, but resident conidia can evade mucocilliary clearance and lodge in the alveoli deep in the lungs, germinating into short hyphae in less than 6 h [ 56 ].…”

Section: Fungal Infectionmentioning

confidence: 99%

Striking Back against Fungal Infections: The Utilization of Nanosystems for Antifungal Strategies

Gao

Liu

et al. 2021

IJMS

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Fungal infections have become a major health concern, given that invasive infections by Candida, Cryptococcus, and Aspergillus species have led to millions of mortalities. Conventional antifungal drugs including polyenes, echinocandins, azoles, allylamins, and antimetabolites have been used for decades, but their limitations include off-target toxicity, drug-resistance, poor water solubility, low bioavailability, and weak tissue penetration, which cannot be ignored. These drawbacks have led to the emergence of novel antifungal therapies. In this review, we discuss the nanosystems that are currently utilized for drug delivery and the application of antifungal therapies.

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Section: Fungal Infectionmentioning

confidence: 99%

Striking Back against Fungal Infections: The Utilization of Nanosystems for Antifungal Strategies

Gao

Liu

et al. 2021

IJMS

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“…The renovation and remodeling of buildings are usually the main sources of indoor air pollutants (Lioy et al 1992;Turner 1998;Yiin et al 2004;Bogovski et al 2007;Young et al 2008;Hasegawa et al 2009), with dust, heavy metals, fibers, gases, bio-aerosols, volatile and semi-volatile organic compounds the major air pollutants generated by renovation actions (Hameed et al 2004). Exposure to lead, for example, can occur when leadbased paints are improperly removed from surfaces through sanding, dry scraping, flame burning and demolition (Sen et al 2002;Farfel et al 2003;Bernstein et al 2008).…”

Section: Introductionmentioning

confidence: 99%

Composition of heavy metals and airborne fibers in the indoor environment of a building during renovation

Latif

Baharudin

Velayutham

et al. 2010

Environ Monit Assess

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The renovation of a building will certainly affect the quality of air in the vicinity of where associated activities were undertaken, this includes the quality of air inside the building. Indoor air pollutants such as particulate matter, heavy metals, and fine fibers are likely to be emitted during renovation work. This study was conducted to determine the concentration of heavy metals, asbestos and suspended particulates in the Biology Building, at the Universiti Kebangsaan, Malaysia (UKM). Renovation activities were carried out widely in the laboratories which were located in this building. A low-volume sampler was used to collect suspended particulate matter of a diameter size less than 10 μm (PM₁₀) and an air sampling pump, fitted with a cellulose ester membrane filter, were used for asbestos sampling. Dust was collected using a small brush and scope. The concentration of heavy metals was determined through the use of inductively coupled plasma-mass spectroscopy and the fibers were counted through a phase contrast microscope. The concentrations of PM₁₀ recorded in the building during renovation action (ranging from 166 to 542 μg m⁻³) were higher than the value set by the Department of Safety and Health for respirable dust (150 μg m⁻³). Additionally, they were higher than the value of PM₁₀ recorded in indoor environments from other studies. The composition of heavy metals in PM₁₀ and indoor dust were found to be dominated by Zn and results also showed that the concentration of heavy metals in indoor dust and PM₁₀ in this study was higher than levels recorded in other similar studies. The asbestos concentration was 0.0038 ± 0.0011 fibers/cc. This was lower than the value set by the Malaysian Department of Occupational, Safety and Health (DOSH) regulations of 0.1 fibers/cc, but higher than the background value usually recorded in indoor environments. This study strongly suggests that renovation issues need to be considered seriously by relevant stakeholders within the university in order to ensure that the associated risks toward humans and indoor environment are eliminated, or where this is not feasible, minimized as far as possible.

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“…Previous studies have suggested that household renovation releases particulate matter, volatile organic compound (VOCs), lead, sulfate, nitrate, chloride, ammonium, and fungi that deteriorate indoor air quality, damage the immune system and result in bad health outcomes 14‐17 . In their study of Malaysia, Norbäck et al 18 proposed that formaldehyde and BTEX in indoor air were risk factors for fatigue, headache, ocular, and throat symptoms in high school students.…”

Section: Introductionmentioning

confidence: 99%

Associations between household renovation and rhinitis among preschool children in China: A cross‐sectional study

et al. 2020

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During 2010‐2012, we surveyed 40,010 3‐ to 6‐year‐old children in seven Chinese cities (Beijing, Taiyuan, Urumqi, Shanghai, Nanjing, Changsha, and Chongqing). Their parents reported information on household renovation, including the timing of renovation and the choice of materials for walls and floors in the child's room, and the incidence of their child's rhinitis. Multivariate and two‐level (city‐child) logistic regression analyses yielding adjusted odds ratios (AOR) with 95% confidence intervals were performed. Sensitivity analyses stratifying data for location and economic level were also performed. About 48.0% of the children had ever had allergic rhinitis, 41.2% had current allergic rhinitis, and 9.0% had had doctor‐diagnosed rhinitis. Exposure to household renovation during early lifetime (birth to 1‐year‐old) had an AOR of 1.43 (1.04‐1.9) for allergic rhinitis. The incidence of allergic rhinitis was significantly different in children exposed to different floor and wall covering materials. Floor or wall covering material composed of organic materials significantly increased the risk of childhood allergic rhinitis compared with tile flooring or lime wall covering. Oil paint had an AOR of 1.66 (1.28‐2.14) for diagnosed rhinitis compared with lime wall covering. Adding new furniture the year before pregnancy was associated with an AOR of 1.18 (1.10‐1.27) and 1.18 (1.11‐1.25) for lifetime and current rhinitis. Solid wood or tiles/ceramic as floor materials, and using wallpaper, oil paint, or emulsion panels as wall materials were risk factors for doctor‐diagnosed rhinitis. Sensitivity analyses showed that children living in southern or higher economic level China cities were more likely to have allergic rhinitis with household renovation.

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Indoor air quality during renovation actions: a case study

Cited by 44 publications

References 20 publications

Striking Back against Fungal Infections: The Utilization of Nanosystems for Antifungal Strategies

Striking Back against Fungal Infections: The Utilization of Nanosystems for Antifungal Strategies

Composition of heavy metals and airborne fibers in the indoor environment of a building during renovation

Associations between household renovation and rhinitis among preschool children in China: A cross‐sectional study

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