Induced Mild Hypothermia in Children after Brain Injury

Grinkevičiūtė, Dovilė Evalda; Kėvalas, Rimantas

doi:10.1515/revneuro.2009.20.3-4.261

Cited by 10 publications

(5 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…9,16 Grinkevicuite et al reported a high frequency of airway infections in TH-treated children suffering from traumatic or post-hypoxic brain injury. 21 In contrast to our results, Shankaran et al found a nearly equal incidence of infection. 12 A study by Gluckman et al involving 218 infants with neonatal encephalopathy treated with selective head cooling found no significant difference in the frequency of clinically important complications, including infections.…”

Section: Ta B L E 2 Coagulation Parameterscontrasting

confidence: 99%

“…Similarly, other data concerning diagnosed infections during TH on paediatric patients seem inconclusive 9,16 . Grinkevicuite et al reported a high frequency of airway infections in TH‐treated children suffering from traumatic or post‐hypoxic brain injury 21 . In contrast to our results, Shankaran et al found a nearly equal incidence of infection 12 .…”

Section: Discussioncontrasting

confidence: 86%

See 1 more Smart Citation

Necessity of early and continuous monitoring for possible infectious complications in children undergoing therapeutic hypothermia

et al. 2020

View full text Add to dashboard Cite

Aim Since therapeutic hypothermia (TH) is known for its inhibitory effects on leucocyte migration and cytokine synthesis, our aim was to underline the necessity of early monitoring for potential immunomodulatory risks. Methods Using a 13‐year retrospective case‐control study at the paediatric intensive care unit (PICU) of the Medical University in Vienna, all newborn infants and children receiving TH were screened and compared with a diagnosis‐matched control group undergoing conventional normothermic treatment (NT). TH was accomplished by using a non‐invasive cooling device. Target temperature was 32‐34°C. Children with evident infections, a medical history of an immunodeficiency or undergoing immunosuppressive therapy, were excluded. Results During the observational period, 108 patients were screened, 27 of which underwent TH. Culture‐proven infections occurred in 22% of the TH group compared with 4% of the normothermic controls (P = .1). From the second day following PICU admission, median C‐reactive protein (CRP) values were higher in the TH group (day two P = .002, day three P = .0002, day six P = .008). Conclusion Children undergoing TH showed earlier and higher increases in CRP levels when compared to normothermic controls. These data underline the necessity of early and continuous monitoring for possible infectious complications.

show abstract

Section: Ta B L E 2 Coagulation Parameterscontrasting

confidence: 99%

Section: Discussioncontrasting

confidence: 86%

Necessity of early and continuous monitoring for possible infectious complications in children undergoing therapeutic hypothermia

et al. 2020

View full text Add to dashboard Cite

show abstract

“…The associated complications prevent use of hypothermia in routine paediatric neurosurgical practice despite obtaining encouraging results following brain injury. [15] The intraoperative goal is to maintain normothermia and avoid both hypothermia and hyperthermia with application of different methods.…”

Section: Intraoperative Considerationsmentioning

confidence: 99%

Anaesthesia for neurosurgical procedures in paediatric patients

Rath

Dash

2012

Indian J Anaesth

View full text Add to dashboard Cite

Recent advances in neurosurgery, neuromonitoring and neurointensive care have dramatically improved the outcome in patients affected by surgical lesions of central nervous system (CNS). Although most of these techniques were applied first in the adult population, paediatric patients present a set of inherent challenges because of their developing and maturing neurological and physiological status, apart from the CNS disease process. To provide optimal neuroanaesthesia care, the anaesthesiologist must have the knowledge of basic neurophysiology of developing brain and effects of various drugs on cerebral haemodynamics apart from the specialised training on paediatric neuroanaesthesia. This article highlights on the perioperative management of paediatric neurosurgical patients.

show abstract

“…[4] The autoregulation range of blood pressure in normal newborn is narrow between 20 and 60 mmHg. [5] The autoregulatory slope drops and rises significantly at the lower and upper limits of the curve, respectively. Sudden hypotension and hypertension at either end of the autoregulatory curve places the neonate at risk for cerebral ischaemia and intraventricular haemorrhage (IVH), respectively.…”

Section: Introductionmentioning

confidence: 96%

Anaesthesia for Neurosurgical Procedures in Paediatric Patients at Kamineni Institute of Medical Sciences

Sujay¹

2017

jmscr

View full text Add to dashboard Cite

Induced Mild Hypothermia in Children after Brain Injury

Abstract: Mild induced hypothermia can be safely used in pediatric patients after severe traumatic or posthypoxic brain injury. This method may be of benefit while improving outcomes in children.

Cited by 10 publications

References 3 publications

Necessity of early and continuous monitoring for possible infectious complications in children undergoing therapeutic hypothermia

Necessity of early and continuous monitoring for possible infectious complications in children undergoing therapeutic hypothermia

Anaesthesia for neurosurgical procedures in paediatric patients

Anaesthesia for Neurosurgical Procedures in Paediatric Patients at Kamineni Institute of Medical Sciences

Contact Info

Product

Resources

About