Inductively Coupled Plasma Mass Spectrometers

Olesik, John W.

doi:10.1016/b978-0-08-095975-7.01426-1

Cited by 24 publications

(28 citation statements)

References 76 publications

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Section: Sample Introductionmentioning

confidence: 99%

“…Typical transport efficiencies decrease from around 15 % at a sample uptake rate of 0.1 mL/min to around 1.5 % at 1 mL/min [68,69]. At sample uptake rates ≤10 μL/min, transport efficiency can be as high as 100 %, with typical transport efficiencies in open, conical spray chambers or double pass spray chambers of 60 to 80 % [68][69][70]. Transport efficiencies near 100 % are possible for flow rates up to 0.5 mL/min when using some spray chamber designs, including heated spray chambers with solvent vapor removal [71] and unheated spray chambers used with low (~10 μL/min) sample uptake rates [72].…”

Section: Sample Introductionmentioning

confidence: 99%

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Single Particle ICP-MS: Advances toward routine analysis of nanomaterials

et al. 2016

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From its early beginnings in characterizing aerosol particles to its recent applications for investigating natural waters and waste streams, single particle inductively coupled plasma-mass spectrometry (spICP-MS) has proven to be a powerful technique for the detection and characterization of aqueous dispersions of metal-containing nanomaterials. Combining the high-throughput of an ensemble technique with the specificity of a single particle counting technique and the elemental specificity of ICP-MS, spICP-MS is capable of rapidly providing researchers with information pertaining to size, size distribution, particle number concentration, and major elemental composition with minimal sample perturbation. Recently, advances in data acquisition, signal processing, and the implementation of alternative mass analyzers (e.g., time-of-flight) has resulted in a wider breadth of particle analyses and made significant progress toward overcoming many of the challenges in the quantitative analysis of nanoparticles. This review provides an overview of spICP-MS development from a niche technique to application for routine analysis, a discussion of the key issues for quantitative analysis, and examples of its further advancement for analysis of increasingly complex environmental and biological samples. Graphical Abstract Single particle ICP-MS workflow for the analysis of suspended nanoparticles.

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Section: Sample Introductionmentioning

confidence: 99%

Section: Sample Introductionmentioning

confidence: 99%

Single Particle ICP-MS: Advances toward routine analysis of nanomaterials

et al. 2016

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“…Response from PVG of BrO 3 − was enhanced 21-fold relative to its solution nebulization and the corresponding LOD, 0.22 ng/mL, reflected a nearly 10-fold improvement. Taking into account the relative flux of analyte to the two introduction systems wherein supply to the PVG reactor was 3.3 mL/min and that to the nebulizer was 1 mL/ min, and further assuming that the nominal efficiency for sample introduction with the nebulizer is 2%, 14 corresponding sample introduction efficiencies for PVG of Br − and BrO 3 − are nominally 4% and 13%, respectively. The latter figure does not appear to be a remarkable improvement in analytical performance for PVG but when substantial increases in flow rate of sample to the ICP can be utilized without degrading efficiency of generation, significant performance improvements accrue, as evidenced from the above.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

Detection of Bromine by ICP-oa-ToF-MS Following Photochemical Vapor Generation

Sturgeon

2015

Anal. Chem.

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/npsi/ctrl?action=rtdoc&an=21275830&lang=en http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/ctrl?action=rtdoc&an=21275830&lang=fr READ THESE TERMS AND CONDITIONS CAREFULLY BEFORE USING THIS WEBSITE.http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/jsp/nparc_cp.jsp?lang=en Vous avez des questions? Nous pouvons vous aider. Pour communiquer directement avec un auteur, consultez la première page de la revue dans laquelle son article a été publié afin de trouver ses coordonnées. Si vous n'arrivez pas à les repérer, communiquez avec nous à PublicationsArchive-ArchivesPublications@nrc-cnrc.gc.ca. Questions? Contact the NRC Publications Archive team atPublicationsArchive-ArchivesPublications@nrc-cnrc.gc.ca. If you wish to email the authors directly, please see the first page of the publication for their contact information. NRC Publications Archive Archives des publications du CNRCThis publication could be one of several versions: author's original, accepted manuscript or the publisher's version. / La version de cette publication peut être l'une des suivantes : la version prépublication de l'auteur, la version acceptée du manuscrit ou la version de l'éditeur. For the publisher's version, please access the DOI link below./ Pour consulter la version de l'éditeur, utilisez le lien DOI ci-dessous.http://doi.org/10.1021/ac504747aAnalytical Chemistry, 87, 5, pp. 3072-3079, 2015-02-04 Detection of Bromine by ICP-oa-ToF-MS Following Photochemical Vapor Generation Ralph E. Sturgeon* National Research Council of Canada, Measurement Science and Standards, Ottawa, Ontario K1A 0R6, Canada ABSTRACT: A unique flow-through photochemical reactor is utilized for the generation of volatile methyl bromide from aqueous solutions of bromide and bromate ions in a medium of 2% acetic acid containing 3000 μg/mL NH 4 Cl. The volatile product is transported to a thin-film gas−liquid phase separator and directed to an inductively coupled plasma (ICP) tine-offlight mass spectrometer for detection and quantitation using either of the 79 Br or 81 Br isotopes. Utilizing a sample flow rate of 3.3 mL/min and a 13 s irradiation time, a detection limit of 0.14 ng/mL is achieved, yielding a 17-fold enhancement over conventional solution nebulization. The estimated generation efficiency of 95% provides for a significant increase in analyte transport efficiency to the ICP. Precision of replicate measurement is 2.5% (RSD) at 20 ng/mL. The methodology was validated by successful determination of bromine in reference materials, including IRMM (BCR-611) low level bromide in groundwater, NIST SRM 1568b Rice Flour, and SRM 1632 bituminous coal.O nly recently has bromine been identified as an essential trace element, important for the development of collagen in mammals. 1 Current major interest in this element arises from its widespread usage in industrial materials, including fire retardants, agricultural pesticides and pharmaceuticals. Treatment of groundwater by ozonolysis 2 to ensure potability raises concerns over production of bromate disinfection byproducts which...

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“…Inductively coupled plasma-mass spectrometry (ICP-MS) is an advanced technology to analyze more than 70 elements in a solution, and the linear dynamic range can reach 9 orders of magnitude [ 15 ]. It has been widely used in the analysis of trace and ultra-trace inorganic elements in medicine, food, and other industries due to its high sensitivity, simultaneous determination of multiple elements, and strong anti-interference ability [ 16 – 18 ].…”

Section: Introductionmentioning

confidence: 99%

Determination of 18 Trace Elements in 10 Batches of the Tibetan Medicine Qishiwei Zhenzhu Pills by Direct Inductively Coupled Plasma-Mass Spectrometry

Song

Zhang

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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Qishiwei Zhenzhu pills (QSW) was first recorded in the Tibetan medicine classic Si Bu Yi Dian and has been used to treat “Baimai” disease, stroke, paralysis, hemiplegia, cerebral hemorrhage, and other diseases till today. This prescription contains more than 70 medicines including myrobalan, pearl, agate, opal, bezoar, coral, musk, gold, silver, and a mineral mixture Zuotai. As a result, QSW contains a large amount of mercury, copper, lead, and other trace elements. The aim of this study was to determine the 18 trace elements (lithium, beryllium, scandium, vanadium, chromium, manganese, cobalt, nickel, copper, arsenic, strontium, argentum, cadmium, cesium, barium, lead, aurum, and mercury) in 10 batches of QSW produced by 5 pharmaceutical companies (Ganlu Tibetan Medicine Co., Ltd. has 6 different batches) by direct inductively coupled plasma-mass spectrometry (ICP-MS). ICP-MS is a rapid, sensitive, accurate methodology allowing the determination of 18 elements simultaneously. The results showed that each element had an excellent linear relationship in the corresponding mass concentration range. The results showed that the rank order of the elements in QSW was copper > mercury > lead from high to low, with the mass fraction higher than 6000 μg/kg; the mass fractions of argentum, arsenic, manganese, aurum, strontium, barium, chromium, and nickel were in the range of 33–1034 μg/kg; and the mass fractions of vanadium, cobalt, lithium, beryllium, cadmium, scandium, and cesium were lower than 10 μg/kg. The reproducibility from the same manufacturer (Tibet Ganlu Tibetan Medicine Co., Ltd.) was relatively high; however, the element amounts among 5 manufacturers were different, which could affect the efficacy and toxicity of QSW. All in all, ICP-MS can be used as an effective tool for the analysis of trace elements in QSW and standard quality control needs to be enforced across different manufactures.

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Inductively Coupled Plasma Mass Spectrometers

Cited by 24 publications

References 76 publications

Single Particle ICP-MS: Advances toward routine analysis of nanomaterials

Single Particle ICP-MS: Advances toward routine analysis of nanomaterials

Detection of Bromine by ICP-oa-ToF-MS Following Photochemical Vapor Generation

Determination of 18 Trace Elements in 10 Batches of the Tibetan Medicine Qishiwei Zhenzhu Pills by Direct Inductively Coupled Plasma-Mass Spectrometry

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