Infant Pertussis

Bisgard, Kristine M.; Pascual, F. Brian; Ehresmann, Kristen; Miller, Claudia; Cianfrini, Christy; Jennings, Charles E.; Rebmann, Catherine A; Gabel, Julie; Schauer, Stephanie L.; Lett, Susan M.

doi:10.1097/01.inf.0000145263.37198.2b

Cited by 364 publications

(73 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…4,5 Though older children and adults are unlikely to experience severe complications from pertussis, they can act as vectors of infection when in contact with those who are more vulnerable, including unvaccinated or incompletely vaccinated infants and children. 6,7 This article was externally peer reviewed. Submitted 20 October 2016; revised 13 January 2017; accepted 13 January 2017.…”

mentioning

confidence: 99%

Clinical Diagnosis of Bordetella Pertussis Infection: A Systematic Review

2017

View full text Add to dashboard Cite

Background: Bordetella pertussis (BP) is a common cause of prolonged cough. Our objective was to perform an updated systematic review of the clinical diagnosis of BP without restriction by patient age.Methods: We identified prospective cohort studies of patients with cough or suspected pertussis and assessed study quality using QUADAS-2. We performed bivariate meta-analysis to calculate summary estimates of accuracy and created summary receiver operating characteristic curves to explore heterogeneity by vaccination status and age.Results

show abstract

mentioning

confidence: 99%

Clinical Diagnosis of Bordetella Pertussis Infection: A Systematic Review

2017

View full text Add to dashboard Cite

show abstract

“…20 Reasons for this include: waning immunity following both natural infection and immunisation, 11,20,21,22 The increase in pertussis in adolescents and adults in NSW is of concern because they may serve as reservoirs of infection for partially immunised infants. 13,20,21,25 In studies from the United States, 26 France, 27 adolescents with a coughing illness of at least 1 week's duration have pertussis. 30,31 This proportion may change depending on the nature of pertussis activity at the time; during pertussis epidemics this may be higher than at other times.…”

Section: Discussionmentioning

confidence: 99%

EPIREVIEW: Pertussis in New South Wales, 1993–2005: the impact of vaccination policy on pertussis epidemiology

Viney

McAnulty

Campbell‐Lloyd

2007

NSW Public Health Bull.

View full text Add to dashboard Cite

Pertussis, or whooping cough, is a highly contagious disease caused by the bacteria Bordetella pertussis. The disease is characterised by paroxysmal cough, inspiratory whoop and post-tussive vomiting. 1 Pertussis is transmitted via direct contact with discharges from the respiratory tract of infected individuals (probably via droplets), and the incubation period is 9-10 days on average. 2 A secondary attack rate of 90% has been recorded in non-immune household contacts. 2 Worldwide, the incidence of pertussis has been reported to be highest in children under 5 years, except where infant vaccination programs have achieved consistently high vaccination rates. 2 In NSW, there have been several changes to the immunisation schedule affecting pertussis vaccination in recent years. From 1985, a combined whole cell diphtheria, tetanus and pertussis vaccine (DTPw) was included in the immunisation schedule at ages 2, 4 and 6 months, with a booster at 18 months. 3 In 1994, a fifth dose was introduced Methods: Surveillance data from the NSW Notifiable Diseases Database was reviewed for the period. Results: 35695 cases of pertussis were notified; annual incidence rates varied from 18.4 to 84.2 per 100000 people. The highest rates of pertussis were consistently found in infants aged 0-6 months. Rates of disease in other age groups changed markedly over the study period, with high rates currently observed in adult age groups. Conclusions: New strategies may be needed to control pertussis in infants and in adults who now comprise the largest proportion of cases.

show abstract

“…99 Finally, besides mothers, several other family members are also potential sources of infection. 91 In fact, post-partum immunization alone does not seem to be sufficient to reduce pertussis incidence in newborns. 100 While post-partum immunization can be logistically affordable if entrusted to the staff providing assistance to delivery, the immunization of other family members can be a problem.…”

Section: Strategies For the Prevention Of Pertussismentioning

confidence: 99%

“…A further integration in the immunization approach against pertussis is the introduction of a booster dose in adolescents who represent the age group in which the issue of waning immunity starts to appear. Since adolescence is a significant source of infection in the epidemiology of this disease, 91 immunization in this age group has an indirect impact on the protection of infants. The introduction of a booster dose in adolescents has been suggested to be one of the strategies with the greatest impact on pertussis infection control for a long time.…”

Section: Strategies For the Prevention Of Pertussismentioning

confidence: 99%