Infantile colic revisited.

Illingworth, R. S.

doi:10.1136/adc.60.10.981

Cited by 117 publications

(41 citation statements)

References 40 publications

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“…Infantile colic is characterized by bouts of excessive prolonged crying for 2-3 h or more [8,11,13,16]. In our study, colic/crying occurred in 42% of the infants with CMPI.…”

Section: Discussionmentioning

confidence: 60%

Cow's milk protein intolerance in infants under 1 year of age: A prospective epidemiological study

et al. 1993

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Incidence and clinical manifestation of cow's milk protein intolerance (CMPI) were studied in 1158 unselected newborn infants followed prospectively from birth to 1 year of age. No food changes were required in 914 infants who were used as healthy controls. When CMPI was suspected (211 infants), diagnostic dietary interventions according to a standard protocol were performed. After exclusion of lactose intolerance, two positive cow's milk elimination/challenge tests were considered diagnostic of CMPI. Two hundred and eleven symptomatic infants were examined for possible CMPI. A large group of 80 infants improved on a lactose reduced formula. In 87/211 infants CMPI was excluded (sick controls). Finally CMPI was proven in 26 infants. The calculated incidence rate for CMPI was 2.8%. The principal symptoms in infants with CMPI were gastrointestinal, dermatological and respiratory in 50%, 31% and 19% respectively. A positive family history for atopy (first or second degree relatives) was more frequent in either CMPI infants (65%), or sick controls (63%) when compared to either healthy controls (35%) or infants improving on a low lactose formula (51%). Differences between patients with CMPI and sick controls were only found for the presence of atopy in at least 2 first degree relatives [(5/26 in CMPI infants and 4/87 in sick controls (P < 0.05)] and for multiorgan involvement [10/26 infants with CMPI as opposed to 12/87 in the sick control group (P < 0.02)]. These statistical differences are too weak to be of clinical value.

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“…Infantile colic is characterized by bouts of excessive prolonged crying for 2-3 h or more [8,11,13,16]. In our study, colic/crying occurred in 42% of the infants with CMPI.…”

Section: Discussionmentioning

confidence: 60%

Cow's milk protein intolerance in infants under 1 year of age: A prospective epidemiological study

et al. 1993

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“…They start in the first weeks of life and generally cease at the age of 4 to 5 months. 1 To discriminate excessive crying from normal crying, a time criterion is often used: at least 3 hours per day for at least 3 days a week for a minimum of 3 weeks. 2 Infantile colic can be thought of as a syndrome or as a symptom.…”

mentioning

confidence: 99%

Infantile Colic: Crying Time Reduction With a Whey Hydrolysate: A Double-Blind, Randomized, Placebo-Controlled Trial

et al. 2000

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“…Recovery from birth and extra-uterine adjustment may make such demands on newborn infants that individual differences in responsivity are difficult to detect before 1 week of age. This might also account for the common clinical observation that colic has its onset at around 2 weeks of age (Illingworth 1985, Pauli-Pott et al 2000.…”

Section: Discussionmentioning

confidence: 89%

Individual differences in responsivity to a neurobehavioural examination predict crying patterns of 1‐week‐old infants at home

James‐Roberts

Bargn

Peter

et al. 2003

Develop Med Child Neuro

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Unexplained crying in infants aged 1 to 3 months is a common concern for Western parents and health services. This study examined the hypothesis that the crying is due to high infant responsivity, and provides evidence about the types of stimulation that trigger crying in infants who present with high responsivity. The sample included 93 eight‐day‐old infants from a community sample (47 females, 46 males; mean birth weight 3457g; mean gestation 39.4 weeks; mean Apgar scores 8.28 at 1 minute and 9.59 at 5 minutes). Infants were tested for their response to two standard, mildly challenging, procedures: a neurobehavioural test involving undressing, putting down, and handling, and the Guthrie test, involving a painful heel prick to obtain a blood sample. The infants’ crying over 24 hours was recorded in parental diaries. Newborn infants who exhibited high responsivity during the neurobehavioural assessment cried, rather than fussed, the most at home. High responsivity during the neurobehavioural assessment also predicted those infants who cried a lot and met a definition of ‘colic’ at home. The findings support the responsivity hypothesis and show that infants with high responsivity are upset by undressing, putting down, and sustained handling. Explanations for this and implications for the management of infant crying and colic are discussed.

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Infantile colic revisited.

Cited by 117 publications

References 40 publications

Cow's milk protein intolerance in infants under 1 year of age: A prospective epidemiological study

Cow's milk protein intolerance in infants under 1 year of age: A prospective epidemiological study

Infantile Colic: Crying Time Reduction With a Whey Hydrolysate: A Double-Blind, Randomized, Placebo-Controlled Trial

Individual differences in responsivity to a neurobehavioural examination predict crying patterns of 1‐week‐old infants at home

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