Infantile Hemangioendothelioma

Roos, Justus E.; Pfiffner, Roger; Stallmach, Thomas; Stuckmann, G.; Marinček, Borut; Willi, Ulrich

doi:10.1148/rg.236035024

Cited by 32 publications

(49 citation statements)

References 5 publications

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“…Ultrasonography is generally regarded as the first step. Ultrasonographic imaging of infantile "hemangioendothelioma" frequently reveals well-circumscribed hypoechoic lesions and abnormal large vascular structures in the liver, infarct, hemorrhage, calcified focus, and fibrous tissue (12). In our case, as shown in the literature, while smooth-contoured hypoechoic solid nodules were observed by ultrasonography in the liver, the MRI examination showed that these lesions were multiple hemangiomas showing diffuse contrast material involvement.…”

Section: Discussionsupporting

confidence: 78%

“…Imaging techniques such as USG, color Doppler USG, CT, MRI, and angiography are used for the diagnosis (12)(13)(14). Ultrasonography is generally regarded as the first step.…”

Section: Discussionmentioning

confidence: 99%

“…Visualization methods are very useful in the diagnosis. While single or multiple hypoechoic calcified lesions in the liver are observed in ultrasonography, computerized tomography, magnetic resonance imaging, and liver biopsy, which is an invasive method, are helpful in diagnosis (12)(13)(14). Histologically, this tumor, which is in a benign appearance, causes severe life-threatening complications such as heart failure at a rate of 70% (10,14).…”

Section: Introductionmentioning

confidence: 99%

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A Rare Cause of Hepatomegaly: Infantile Hepatic Hemangiomendothelioma

Gümüştekin¹,

Urgancı²,

Vural³

2016

JAREM

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Infantile hepatic hemangiomendothelioma, a bening vascular neoplasia derived from endothelial cells, is the most common newborn tumor located in the liver. The tumor has female predominancy. Mostly, it is associated with a good prognosis and may show spontaneous regression by the time the infant is 1 year of age. Although most of the patients are asymptomatic, abdominal mass, hepatomegaly, jaundice, nausea, and vomiting can be encountered among common clinical findings. Herein, a 1.5-month-old boy with abdominal distention was referred to our gastroenterology unit for hepatomegaly. Non-invasive diagnostic modalities revealed infantile hepatic hemangioendothelioma.

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Section: Discussionsupporting

confidence: 78%

“…Imaging techniques such as USG, color Doppler USG, CT, MRI, and angiography are used for the diagnosis (12)(13)(14). Ultrasonography is generally regarded as the first step.…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A Rare Cause of Hepatomegaly: Infantile Hepatic Hemangiomendothelioma

Gümüştekin¹,

Urgancı²,

Vural³

2016

JAREM

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“…A review of the literature, however, identified several examples of solitary liver haemangiomas, compatible with RICH, which were published before the distinction between IH and RICH became widely known [15][16][17][18][24][25][26][27][28][29][30][31].…”

Section: Discussionmentioning

confidence: 99%

Rapidly involuting congenital haemangioma (RICH) of the liver

et al. 2012

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RICH should be suspected in neonates who present with a solitary liver lesion and normal-for-age serum alpha-fetoprotein. Serial US scans should be used to confirm a progressive shrinkage of the lesion. Corticosteroids and β2-adrenergic antagonists have no proven effect in treating RICH. If the lesion grows, percutaneous needle biopsy is recommended to exclude a malignant tumour and to direct further management. Infants with cardiac failure should be treated medically. Embolization (with or without needle biopsy) should only be performed when this strategy fails.

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“…Large solitary lesions are often associated with central hemorrhage, necrosis, calcification, thrombosis, or fibrosis. 3 A solid lesion with a heterogeneous echotexture is typically noted on sonograms ( Figure 3A). CT typically shows a lowattenuation solid lesion with peripheral enhancement ( Figure 3B).…”

Section: Infantile Hemangioendotheliomamentioning

confidence: 99%