Infarto agudo al miocardio en un hombre joven sin ateromatosis coronaria, como forma de presentación de síndrome antifosfolípido primario: Caso clínico

O, Marisol Jurado; Durán, Josefina; Martínez, Alejandro; Castellón, José Miguel; Gutiérrez, Miguel

doi:10.4067/s0034-98872009001100011

Rev. méd. Chile

2009

DOI: 10.4067/s0034-98872009001100011

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Infarto agudo al miocardio en un hombre joven sin ateromatosis coronaria, como forma de presentación de síndrome antifosfolípido primario: Caso clínico

Marisol Jurado O

Josefina Durán

Alejandro Martínez

et al.

Abstract: Infarto agudo al miocardio en un hombre joven sin ateromatosis coronaria, como forma de presentación de síndrome antifosfolípido primario. Caso clínico

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Cited by 3 publications

References 21 publications

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Antiphospholipid syndrome combined with acute coronary syndrome

Yuan

Wang²,

Liu³

2018

Medicine

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Rationale:Antiphospholipid syndrome (APS) combined with acute coronary syndrome (ACS) is rarely reported.Patient concerns:One male patient with APS was admitted to our hospital, who had recent unstable angina (UA).Diagnosis:The preliminary diagnosis of ACS and UA (BraunwaldiB) was then made.Interventions:This patient received secondary preventative therapy for coronary heart disease (CHD) in combination with percutaneous transluminal coronary angioplasty (PTCA) and implantation of NeoVas Bioresorbable Coronary Scaffold.Outcomes:The patient was followed up, without new UA episodes were observed at 6 months, 1 year, and 2 year after surgery, respectively.Lessons:It was thus concluded that percutaneous coronary intervention (PCI) is effective for APS patients and NeoVas scaffold implantation is presumed safe.

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Antiphospholipid syndrome combined with acute coronary syndrome

Yuan

Wang²,

Liu³

2018

Medicine

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Effective Management of Acute Coronary Thrombosis in a Young Woman with Lupus Using Aggressive Medical Therapy

2011

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Systemic lupus erythematosus is a chronic inflammatory disorder that predisposes to acute coronary thrombosis. To demonstrate how the pathophysiology of lupus-mediated coronary events may be unique, we offer the case and management of a young woman with lupus who presented with acute myocardial infarction. She was initially managed with medical therapy including the standard regimen of aspirin, heparin, and clopidogrel. Despite a Thrombolysis in Myocardial Infarction risk score of only 2, she was also given eptifibatide infusion because of clinical concerns. Repeated cardiac catheterization showed marked regression of the thrombus, and coronary fractional flow reserve calculation demonstrated full recovery of coronary vasculature with this therapy. This case demonstrates effective management of life-threatening coronary thrombosis with medical therapy only in a young woman with lupus. We briefly review the pathophysiology of acute coronary thrombosis in lupus patients and distinguish this from the more common process of age-related atherosclerosis. Given the lack of evidence in this specific population, we discuss a pathophysiology-based clinical decision-making tool. Assessing clinical risk factors and using technologies such as intravascular ultrasound can help make the correct treatment decision.

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Intravascular Images of Coronary Stenosis with Multiple Channels in a Patient with Antiphospholipid Syndrome: The Optical Coherence Tomography Findings

Ito

Hasuo

2017

Intern. Med.

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Intravascular images of coronary stenosis by antiphospholipid syndrome (APS) would be beneficial to understand the mechanism of this disease. A 59-year-old woman with APS/systemic lupus erythematosis (SLE) underwent emergent coronary angiography which revealed stenosis with micro channels in the proximal left anterior descending artery. According to optical coherence tomography (OCT), the central lumen was surrounded by a thick septum with a homogenous and high intensity. Multiple small channels existed near the vessel wall with diffuse intimal hyperplasia. White thrombi were floating distal to the stenosis. Intravascular images obtained by optical coherence tomography (OCT) revealed the microstructure of complex coronary stenosis, which had ambiguous findings on angiography and intravascular ultrasound (IVUS) in an acute coronary syndrome (ACS) patient with APS/SLE.

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Infarto agudo al miocardio en un hombre joven sin ateromatosis coronaria, como forma de presentación de síndrome antifosfolípido primario: Caso clínico

Abstract: Infarto agudo al miocardio en un hombre joven sin ateromatosis coronaria, como forma de presentación de síndrome antifosfolípido primario. Caso clínico

Cited by 3 publications

References 21 publications

Antiphospholipid syndrome combined with acute coronary syndrome

Antiphospholipid syndrome combined with acute coronary syndrome

Effective Management of Acute Coronary Thrombosis in a Young Woman with Lupus Using Aggressive Medical Therapy

Intravascular Images of Coronary Stenosis with Multiple Channels in a Patient with Antiphospholipid Syndrome: The Optical Coherence Tomography Findings

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