Infection and Allergy Incidence in Ambulatory Surgery Patients Using White Petrolatum vs Bacitracin Ointment

Smack, David Phillips; Harrington, Allan C.; Dunn, Cary L.; Howard, Robin S.; Szkutnik, Albert J.; Krivda, Steven J.; Caldwell, J. B.; James, William D.

doi:10.1001/jama.1996.03540120050033

Cited by 213 publications

(92 citation statements)

References 29 publications

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“…7–10 A recent article proposes that triple antibiotic ointment may prove an attractive alternative to oral antibiotics in select cases of skin wound management because resistance does not develop readily. 11 Then again, in a previous study by Smack et al, 12 no clinically significant differences in postoperative infection rates or wound healing were found between those treated with white petrolatum and bacitracin ointment.…”

Section: Discussionmentioning

confidence: 81%

Allergic Dermatitis Due to Topical Antibiotics

Shahbazian¹,

Hartzell²,

Pandey³

et al. 2012

WestJEM

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Section: Discussionmentioning

confidence: 81%

Allergic Dermatitis Due to Topical Antibiotics

Shahbazian¹,

Hartzell²,

Pandey³

et al. 2012

WestJEM

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“…More recent studies have shown that wounds treated with petrolatum compared with those treated with a topical antibiotic have no increased incidence of infection and heal at the same rate 47 . Zuwkowski et al 41 noted similar bacterial counts and rates of infection in phenol peel sites treated with petroleum gauze and bacitracin ointment.…”

Section: Discussionmentioning

confidence: 99%

Care before and after Laser Skin Resurfacing. A Survey and Review of the Literature

Duke

Grevelink

1998

Dermatologic Surgery

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Many options are appropriate, based on data from past studies, for pre- and postresurfacing skin care. Approximately 73% of the results of the survey correlate with information from the literature. Past studies do provide information to help us select interventions that can improve wound healing and the final cosmetic outcome. Further studies involving resurfacing patients may clarify some of the more complex wound care issues, such as oral prophylactic antibiotics, hydroquinone, and topical vitamins C and E.

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“…One study suggests that white petrolatum is a safe and effective wound care alternative to bacitracin, which may be especially useful in patients with known sensitizations. The study demonstrated that in 922 patients, 9 (2%) patients in the white petrolatum group versus 4 (0.9%) in the bacitracin group developed postprocedure infections 17 . In addition, there was no clinically significant difference in healing between the groups on Days 1, 7, or 28 17 .…”

Section: Bacitracinmentioning

confidence: 94%

Topical Antibacterial Agents for Wound Care: A Primer

et al. 2003

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Although often overlooked, topical antibiotic agents play an important role in dermatology. Their many uses include prophylaxis against cutaneous infections, treatment of minor wounds and infections, and elimination of nasal carriage of Staphylococcus aureus. For these indications, they are advantageous over their systemic counterparts because they deliver a higher concentration of medication directly to the desired area and are less frequently implicated in causing bacterial resistance. The ideal topical antibiotic has a broad spectrum of activity, has persistent antibacterial effects, and has minimal toxicity or incidence of allergy.

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Infection and Allergy Incidence in Ambulatory Surgery Patients Using White Petrolatum vs Bacitracin Ointment

Cited by 213 publications

References 29 publications

Allergic Dermatitis Due to Topical Antibiotics

Allergic Dermatitis Due to Topical Antibiotics

Care before and after Laser Skin Resurfacing. A Survey and Review of the Literature

Topical Antibacterial Agents for Wound Care: A Primer

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