Infections With Mycobacterium marinum

Synovial biopsy

“…Nevertheless, all mycobacterium infections are not of tuberculous origin, and a notable exception is synovitis produced by M. marinum, which involves the tendon sheaths, bones and joints [2,6,13]. In this infection the changes vary from the common nonspecific inflammation to the granulomatous response, with or without caseation.…”

Mycobacterium marinuminfections in man

“…Although infection by M. marinum induces dermal reactivity to skin-testing reagents prepared from the organism in some patients the size of the reaction is similar to that induced by standard PPD or to analogous reagents prepared from other slowly-growing mycobacteria (Judson & Feldman, 1974;Jolly & Seabury, 1972;Schaefer, Blatman & Bravo, 1962). Accordingly, skin testing is of little value in this infection.…”

“…Jolly & Seabury (1972) mention one infection after an 'abrasion on asphalt' in a school yard, two following injuries from rose thorns and one after a contusion related to an electrical installation. Another 'asphalt' case was reported by Arai, Nakajima & Nagai (1984): a Japanese lady sustained a minor injury when she stumbled on an asphalt road outside a fish shop and her lesions became infected.…”

“…Examples of these therapies are given by Wolinsky, Gomez & Zimpfer (1972);Loria (1976);and Kirk & Kaminsky (1976). Jolly & Seabury (1972) described 31 cases seen in America by local clinicians who carried out their own therapies; they reported that in 13 excision was performed, including one amputation. Heat lamps were used in two cases, and chemotherapy (unspecified) in seven.…”

Recommendations for Health Monitoring and Reporting for Zebrafish Research Facilities

“…that are known to infect zebrafish are potentially zoonotic; of these, Mycobacterium marinum has been most frequently implicated in zoonotic infections of immunocompetent individuals. [14][15][16][17] Facility managers, veterinarians, and animal handlers should also be aware of potential emerging agents that may pose an unidentified risk to the facility or may impact the international transfer of animals. When determining which agents to monitor, methods, frequency of testing, and knowledge of the biology of the agents are essential.…”