Infectious complications in infants with gastroschisis: an 11-year review from a referral hospital in southern Thailand

Sangkhathat, Surasak; Patrapinyokul, Sakda; Chiengkriwate, Piyawan; Chanvitan, Prasin; Janjindamai, Waricha; Dissaneevate, Supaporn

doi:10.1016/j.jpedsurg.2007.10.026

Cited by 14 publications

(9 citation statements)

References 23 publications

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“…CRI complicated the hospital course in 14% of our cases, a rate that is less than recent single-institution reports from Thailand and Great Britain [10,11]. While the method of catheter placement did not affect the rate of CRI, the duration of catheter placement did-a finding that is consistent with previous reports in the literature [12].…”

Section: Catheter-related Infections (Cri)supporting

confidence: 88%

“…Nonetheless, neonates with gastroschisis have prolonged hospital admissions and consume considerable hospital resources [9]. Infectious complications have been shown to contribute significantly to the morbidity and mortality of patients with gastroschisis [3,10]. While our study confirms that the development of a CRI or WI is associated with an increased length of stay, it remains unclear whether development of an infectious complication is a cause or an effect of this prolonged NICU admission.…”

Section: Discussionsupporting

confidence: 51%

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Infectious complications in the management of gastroschisis

et al. 2011

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Section: Catheter-related Infections (Cri)supporting

confidence: 88%

Section: Discussionsupporting

confidence: 51%

Infectious complications in the management of gastroschisis

et al. 2011

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“…We identified a neonatal mortality rate of 6 (2%) in the simple group which is similar to other studies [12] and which is usually attributed to associated anomalies or complications of initial surgical intervention. Although in less well-developed health care settings, this rate is much higher and is attributed to sepsis, shock, and intestinal ischemia [19], this study suggests that this mortality rate could still be reduced further in the United Kingdom. The true overall mortality rate will include in utero death and termination, as identified from obstetric data sources, deaths related to complications of neonatal treatment, and a later peak in early infancy caused by IFALD and the complications of short bowel syndrome or adhesive small bowel obstruction.…”

Section: Discussionmentioning

confidence: 72%

Gastroschisis: a national cohort study to describe contemporary surgical strategies and outcomes

Owen

Marven

Johnson

et al. 2010

Journal of Pediatric Surgery

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“…However, preformed silos are expensive and have been largely unavailable in LMICs and hence alternative strategies have been devised 11. Examples include use of an Alexis Wound Retractor as an alternative to the preformed silo, primary reduction at the cotside (Bianchi technique) and umbilical turban and flap closure 21–28.…”

Section: Introductionmentioning

confidence: 99%

Improving outcomes for neonates with gastroschisis in low-income and middle-income countries: a systematic review protocol

Wright

Langer

Norman

et al. 2018

bmjpo

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IntroductionThere is a significant disparity in outcomes for neonates with gastroschisis in high-income countries (HICs) compared with low-income and middle-income countries (LMICs). Many LMICs report mortality rates between 75% and 100% compared with <4% in HICs.AimTo undertake a systematic review identifying postnatal interventions associated with improved outcomes for gastroschisis in LMICs.Methods and analysisThree search strings will be combined: (1) neonates; (2) gastroschisis and other gastrointestinal congenital anomalies requiring similar surgical care; (3) LMICs. Databases to be searched include MEDLINE, EMBASE, Scopus, Web of Science, ProQuest Dissertations and Thesis Global, and the Cochrane Library. Grey literature will be identified through Open-Grey, ClinicalTrials.gov, WHO International Clinical Trials Registry and ISRCTN registry (Springer Nature). Additional studies will be sought from reference lists of included studies. Study screening, selection, data extraction and assessment of methodological quality will be undertaken by two reviewers independently and team consensus sought on discrepancies. The primary outcome of interest is mortality. Secondary outcomes include complications, requirement for ventilation, parenteral nutrition duration and length of hospital stay. Tertiary outcomes include service delivery and implementation outcomes. The methodology of the studies will be appraised. Descriptive statistics and outcomes will be summarised and discussed.Ethics and disseminationEthical approval is not required since no new data are being collected. Dissemination will be via open access publication in a peer-reviewed medical journal and distribution among global health, global surgery and children’s surgical collaborations and international conferences.ConclusionThis study will systematically review literature focused on postnatal interventions to improve outcomes from gastroschisis in LMICs. Findings can be used to help inform quality improvement projects in low-resource settings for patients with gastroschisis. In the first instance, results will be used to inform a Wellcome Trust-funded multicentre clinical interventional study aimed at improving outcomes for gastroschisis across sub-Saharan Africa.PROSPERO registration numberCRD42018095349.

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Infectious complications in infants with gastroschisis: an 11-year review from a referral hospital in southern Thailand

Cited by 14 publications

References 23 publications

Infectious complications in the management of gastroschisis

Infectious complications in the management of gastroschisis

Gastroschisis: a national cohort study to describe contemporary surgical strategies and outcomes

Improving outcomes for neonates with gastroschisis in low-income and middle-income countries: a systematic review protocol

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