“…Since the 14th century, quarantine has been the major disease-control strategy, including isolation, sanitary cordons, bills of health issued to ships, fumigation, disinfection, and regulation of groups of persons who were believed to be responsible for spreading the infection ( 25 ). Also, if the duration of the quarantine is compared with the incubation periods of infectious diseases (e.g., cholera, plague, yellow fever, smallpox), the isolation period overlapped their incubation period ( 26 , 27 ). During epidemics, the urban health authorities adopted social interventions and traditional health tools, such as quarantine of travelers who had contact with infected persons or who came from a place where the disease was endemic or epidemic ( 28 ).…”