Infectious Etiologies of Transient Neutropenia in Previously Healthy Children

Abstract

Neutropenia in previously healthy children in Kuwait is caused by demonstrable infections in 55% of cases. Majority of children will recover their ANC completely within 1 month without significant infectious complications.

Clinical Presentations of HHV-6 Infection in Infants and Children in Kuwait: A Retrospective Study

“…In addition, four patients had single infection with Parvovirus B19, Enterovirus, CMV and Enterovirus, respectively. Our results are in agreement with the study of Hussain et al (2012), which showed that neutropenia in previously healthy children in Kuwait was caused by demonstrable infection in 55% of cases: HHV-6, 30%; Enterovirus, 23%; Influenza A H1N1, 13%; Parvovirus, 10%; EBV, 10%; UTI by Eshcherichia coli, 7%; Adenovirus, 7% by [14].…”

“…This result is in agreement with another study by Hussain et al (2012), where they investigated the infectious causes of isolated transient neutropenia in previously healthy children. They showed that HHV-6 infection was the leading cause of transient neutropenia in previously healthy children in Kuwait [14]. A study by Karavanaki et al (2006) showed that HHV-6 was associated with neutropenia in 2 of 24 pre-viously healthy children [22].…”

“…From a study by Hussain et al [14], where they investigated the infectious etiologies of neutropenia among children in Kuwait, there has been no published data on the spectrum of signs and symptoms developed as a result of HHV-6 infection in infants and children in Kuwait. Therefore, this study describes the clinical manifestations and syndromes associated with HHV-6 infection among infants and children in Kuwait.…”

Neutropénies de découverte fortuite chez l’enfant : diagnostic et suivi

“…La neutropénie était plus fréquente chez l'enfant que chez l'adulte, la prévalence étant toutefois très probablement surestimée, variable en fonction de l'âge. Dans notre étude, 52 % des enfants présentant une neutropénie étaient âgés de moins de 2 ans, ce qui confirme la fréquence relativement importante des neutropénies chez le nourrisson, constatée dans la majorité des études disponibles [5,7,9,10,17,18]. Pettiti et al se sont intéressés à l'incidence des neutropénies [ ( F i g u r e _ 2 ) T D $ F I G ] [ ( F i g u r e _ 3 ) T D $ F I G ] inférieures à 0,5 Â 10 9 /L dans une population ambulatoire de patients, en incluant les sujets sur des critères biologiques, comme dans notre étude [12].…”

Isolated neutropenia in children: from the pediatrician to a hematologist (literature review)

“…Транзиторная, или острая, изолирован-ная нейтропения наиболее часто ассоциирована с ви-русными инфекциями [6,7]. В табл.…”