Infective endocarditis in hemodialysis patients: clinical features, echocardiographic data and outcome

Abstract

In this largest reported confirmed IE series in dialysis patients in a developing country, mortality was very high; mitral valve was the most commonly affected valve. Staphylococcus species were the major causative organisms.

Surgical Outcome in Hemodialysis Patients with Active-Phase Infective Endocarditis

“…Reported mortality of HD patients who underwent operation during the active phase of IE is high, [2][3][4] and perioperative management should be carefully planned based on previous experience. In our present study, clinical characteristics specific to our HD patients were pacemaker implantation is predicted after weaning from cardiopulmonary bypass (CPB), epicardial permanent pacing wires (atrial and ventricular) should be implanted intra-operatively, because a permanent intravascular device is a potential risk for recurrent IE in HD patients.…”

“…1) Several previous studies have demonstrated high postoperative mortality (11%-80%) in HD patients who require surgical intervention for IE, [2][3][4] however, little information is available on the preoperative management of these patients.…”

“…1) Several previous studies have demonstrated high postoperative mortality (11%-80%) in HD patients who require surgical intervention for IE, [2][3][4] however, little information is available on the preoperative management of these patients.Here, to improve preoperative management in HD patients requiring surgical intervention for IE, we reviewed surgical experience at our institution over a 10-year period to elucidate the characteristics of chronic HD patients requiring surgery during the active phase of IE. We also reviewed long-term outcomes in these HD patients.…”

Clinical Implications of Circulating Microbiome in Cardiovascular Disease Patients

“…The implications of bacteremia in CVDs have been briefly outlined in Figure 1 and tabulated in Table 1. Large vegetation Congestive heart failure and stroke [59] Mitral and aortic valve vegetation Abscess formation [60] Bi-prosthetic valve infections Valve ring abscess and cuspal infections [62] Acute bacterial endocarditis Valve ring abscesses [63,64] and paravalvular leakage [66,67] Xenograft or mechanical valves Recurrent infections [79] Circulating endotoxemia Congestive heart failure [89,90] …”

“…ESRD patients receiving chronic hemodialysis were particularly prone to non-nosocomial IE [60][61][62] than those receiving peritoneal dialysis [63]. S. aureus and MRSA blood stream infections were more prevalent in hemodialysis patients [64].…”