Infective Endocarditis in the Aging Patient

Cantrell, Mira; Yoshikawa, Thomas T.

doi:10.1159/000212651

Cited by 36 publications

(17 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Heart murmurs in elderly may be wrongly attributed to the underlying valvular calcification and therefore not taken into consideration. Sometimes, endocarditis in the elderly may be present with a stroke syndrome, rheumatologic complaints, or peripheral nervous system abnormalities [21, 22]. Studies that used the Duke criteria for diagnosis of endocarditis have not found any relevant differences between elderly and young patients with regard to the frequency of fever, heart failure, embolic events, neurological symptoms, distribution of causative organisms and cerebral deficit at the time of discharge from the hospital [19, 20].…”

Section: Infectionsmentioning

confidence: 99%

Fever of unknown origin in the elderly

Tal

Guller

Gurevich

et al. 2002

Journal of Internal Medicine

View full text Add to dashboard Cite

show abstract

Section: Infectionsmentioning

confidence: 99%

Fever of unknown origin in the elderly

Tal

Guller

Gurevich

et al. 2002

Journal of Internal Medicine

View full text Add to dashboard Cite

show abstract

“…After excluding patients patients. Some of these investigators have reported fewer sympwho were intravenous drug users and patients who had prostoms, longer delays from onset of illness to medical treatment, thetic valves, we assigned the remaining 108 patients to two and higher complication rates among elderly patients with IE groups: elderly patients ( §65 years of age) and younger pathan among younger adult patients [1,2]. Other investigators tients (30 -59 years of age).…”

Section: Previous Investigators Have Drawn Disparate Conclusion Re-mentioning

confidence: 99%

Native Valve Infective Endocarditis in Elderly and Younger Adult Patients: Comparison of Clinical Features and Outcomes with Use of the Duke Criteria and the Duke Endocarditis Database

et al. 1998

View full text Add to dashboard Cite

The effect of age on the presentation and outcome of infective endocarditis (IE) is unclear. Many of the available data are based on analyses of mixed populations of patients including intravenous drug users or those with prosthetic valve endocarditis or native valve IE. We used the Duke criteria to compare the characteristics of 44 episodes of definite native valve IE in elderly patients (> 64 years old) with the characteristics of 64 similarly defined episodes of native valve IE in younger, nonintravenous-drug-using adult patients (> 29 years and < 60 years old). Our data suggest that the clinical presentation, characteristics, and outcome of native valve IE are similar for elderly patients and younger adult patients, although elderly patients were hospitalized an average of 12 days longer. Although we found that the occurrence of renal failure and cerebral embolism during an episode of IE was associated with higher rates of death (odds ratios, 4.8 and 4.0, respectively), age was not a significant contributor to mortality.

show abstract

“…Therefore, delays in diagnosis and treatment may occur and contribute to its mortality. Because comorbid illnesses are common among the elderly, these nonspecific symptoms of endocarditis may be incorrectly attributed to other underlying medical problems 7,16,24 …”

mentioning

confidence: 99%

Infective Endocarditis in the Elderly: Diagnosis and Management

Gregoratos

2003

American J Geri Cardiology

View full text Add to dashboard Cite

Infective endocarditis is seen with increasing frequency in older patients. This increase is due to the general aging of the population, improved survival of patients with congenital and valvular heart disease, and the increasing use of catheters and other prosthetic devices with resulting higher incidence of nosocomial endocarditis. In older patients, infective endocarditis frequently develops in the absence of underlying structural heart disease; atheromatous deposits and mitral annular calcification are two important risk factors in this population. Infective organisms in older patients are frequently enterococci and other gastrointestinal tract bacteria. A marked febrile response is uncommon whereas central nervous system symptoms are more common in older patients. Transesophageal echocardiography can be performed safely and is a major diagnostic tool with sensitivity of more than 90% in detecting vegetations as small as 2-5 mm. Appropriately drawn blood cultures provide bacteriologic diagnosis in 80%-99% of patients. Prolonged antibiotic therapy may be required in many instances depending on the infective organism. Early surgical therapy is advisable for patients who develop heart failure as a result of severe acute aortic valvular regurgitation. Valve replacement surgery can be performed with acceptable mortality and morbidity even in very elderly patients.

show abstract

Infective Endocarditis in the Aging Patient

Cited by 36 publications

References 19 publications

Fever of unknown origin in the elderly

Fever of unknown origin in the elderly

Native Valve Infective Endocarditis in Elderly and Younger Adult Patients: Comparison of Clinical Features and Outcomes with Use of the Duke Criteria and the Duke Endocarditis Database

Infective Endocarditis in the Elderly: Diagnosis and Management

Contact Info

Product

Resources

About