Infective endocarditis

Baig, Wazir; Sandoe, Jonathan

doi:10.7861/clinmedicine.10-2-188

Cited by 4 publications

(10 citation statements)

References 18 publications

(15 reference statements)

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“…The diagnosis of IE is based on a combination of fever, presence of vegetation in echocardiography and positive blood cultures 3 4. Since a persistent low level of bacteraemia is found in patients with IE, the rate of negative blood culture is expected to be below 5% 5 6. Although negative cultures may be associated with a previous use of antibiotics, it may also be seen in fungal infections like Candida , Histoplasma and Aspergillus , and bacterial infections like Legionella , Coxiella and the HACEK group ( Haemophilus species, Actinobacillus actinomycetemcomitans , Cardiobacterium hominis , Eikenella corrodens and Kingella kingae ) 6 7.…”

Section: Discussionmentioning

confidence: 99%

“…Modified Duke criteria were developed using clinical and microbiological findings as well as findings in echocardiography. Systemic embolus is the most common complication of endocarditis involving major arteries and exerting a primary effect on the central nervous system 4 5. Despite appropriate antimicrobial treatment, neurological complications are found in 20–40% of patients 5 8.…”

Section: Discussionmentioning

confidence: 99%

“…Systemic embolus is the most common complication of endocarditis involving major arteries and exerting a primary effect on the central nervous system 4 5. Despite appropriate antimicrobial treatment, neurological complications are found in 20–40% of patients 5 8. Embolic complications frequently develop during the initial stage of IE and prior to presenting to the hospital in particular 9.…”

Section: Discussionmentioning

confidence: 99%

“…Surgical intervention is a potentially life-saving procedure for IE. Surgical treatment is required in 50% of cases 5. Mortality and morbidity are associated with valvular regurgitation, heart failure, development of abscess and embolic complications 5.…”

Section: Discussionmentioning

confidence: 99%

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Infective endocarditis developing serious multiple complications

Güler¹,

Sökmen²,

Meşe³

et al. 2013

BMJ Case Reports

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A 20-year-old female patient with no history of heart disease presented to the hospital with high fever, cough and sputum. On the third day of hospitalisation, left facial paralysis developed and cranial revealed an infarct in the right frontoparietotemporal lobe. Transthoracic echocardiography revealed 1.5 × 2 cm-sized vegetation on the mitral valve and severe mitral regurgitation. On the 11th day of hospitalisation, multiple emboli were shown to be present in the left iliac artery. Since the patient had recurrent septic emboli despite 3 weeks of treatment, a surgical intervention was planned. The vegetation was removed and the mitral valve was replaced by mechanical prostheses. During the postoperative period, acute renal failure developed in the patient. The treatment was completed in 6 weeks with full recovery. This case confirms that infective endocarditis may present with various clinical situations, and that a high index of suspicion and surgical intervention, in addition to aggressive antibiotic therapy, is lifesaving.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Infective endocarditis developing serious multiple complications

Güler¹,

Sökmen²,

Meşe³

et al. 2013

BMJ Case Reports

View full text Add to dashboard Cite

show abstract

“…The basis of this study is the meticulous collection of data over a long time in what is an uncommon disease with protean manifestations, and which is often difficult to diagnose even by experienced cardiologists. Our European colleagues have demonstrated once again the value of effective collaboration and it would be timely to establish a national UK database for infective endocarditis, as we have recently proposed 4. A precedent for collaborative data collection in cardiology in the UK has been demonstrated by the success and clinical impact of the MINAP database of acute coronary syndromes 5.…”

mentioning

confidence: 99%