Infektinduzierte Harnsteine

Abstract

Infection stones make up approximately 15% of urinary stone diseases and are thus an important group. These stones are composed of struvite and/or carbonate apatite. The basic precondition for the formation of infection stones is a urease-positive urinary tract infection. Urease is necessary to split urea into ammonia and CO(2). As a result, ammonia ions can form and at the same time alkaline urine develops, both being preconditions for the formation of struvite and carbonate apatite crystals. When these crystals are deposited infection stones form. Pathogenetically, various risk factors play a role: urinary obstruction, neurogenic bladder, dRTA, and MSK. If these infections are not treated and the stones are not removed, the kidney will be damaged. Modern methods are available for stone removal, e.g., ESWL and/or instrumental urinary stone removal. Here, especially less invasive methods are preferable. Any treatment must be adjusted to the patient individually. Patients should be examined frequently for recurrent urinary tract infections and stone recurrences, and new infections must be resolutely treated. Good therapy and prophylaxis are possible with present-day treatment modalities.

Prevalence of Progression Toward Renal Calculi in Patients Suffering from Urinary Tract Infection: A Cross-Sectional Study

“…The prevalence of stones in the patients with UTI was 19.56% as observed in the present study. However, it was slightly lower (10-15%) as per the study of Hochreiter et al and Bichler et al [17,18].…”

Harnwegsinfektionen und Urolithiasis

“…Typisch sind "SargdeckelKristalle" im Urinsediment. Konventionell radiologisch ist er schwach schattengebend [4,20].…”

“…4 [24]. Restfragmente und Debris sind unbedingt quantitativ zu entfernen, da von den in ihnen eingeschlossenen Bakterien das Rezidiv ausgeht.…”

“…B. veganische/vegetarische Ernährungs-und Trinkgewohnheiten (überwiegend Zitrussäfte, Mineralwässer mit Hydrogenkarbonatkonzentrationen >1500 mg/l), die eine pH-anhebende Wirkung haben und allgemein niedrige 24-hUrinvolumia sind weitere, die Urinchemie ungünstig beeinflussende Risikofaktoren. Eine durch Harnwegsobstruktionen oder aus anderen Ursachen gestörte Urodynamik und neurogene Blasenentleerungsstörungen sind weitere Risikofaktoren der Infektsteingenese [4,22].…”

“…Typisch sind "SargdeckelKristalle" im Urinsediment. Konventionell radiologisch ist er schwach schattengebend [4,20].Bei der Bildung von Struvit steht der Infekt als Risikofaktor im Vordergrund. Die relative Häufigkeit des Struvits beträgt 4-6% [2, 23].…”