2012
DOI: 10.4103/1817-1745.102595
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Infiltrating medulloblastoma in a child mimicking Lhermitte-Duclos disease

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Cited by 6 publications
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“…The imaging appearance of LDD may rarely be mimicked by extensive infiltration of the cerebellar cortex by medulloblastoma. 26,27 Macroscopically, the discrete circumscribed area of thickened folia usually involves only one hemisphere, but extension to involve the vermis also occurs, as in the current case. The gross specimen may exhibit surface pallor or yellow-white discoloration that reflects aberrant molecular layer myelination.…”
Section: Discussionmentioning
confidence: 79%
“…The imaging appearance of LDD may rarely be mimicked by extensive infiltration of the cerebellar cortex by medulloblastoma. 26,27 Macroscopically, the discrete circumscribed area of thickened folia usually involves only one hemisphere, but extension to involve the vermis also occurs, as in the current case. The gross specimen may exhibit surface pallor or yellow-white discoloration that reflects aberrant molecular layer myelination.…”
Section: Discussionmentioning
confidence: 79%
“…The differential diagnosis is very important in these cases as LDD can mimic some high-grade lesions, such as medulloblastoma, which has the same characteristic appearance in MRI (as in our case with restricted diffusion) [ 13 - 15 ]. Another differential diagnosis is pseudotumoral hemicerebellitis, which has been described in three pediatric cases reported by Bosemani et al [ 16 ].…”
Section: Discussionmentioning
confidence: 99%
“…It is very common that diagnosing LDD with radiological findings is possible but Chen et al [11] published a case report of a medulloblastoma at the posterior fossa which showed an abnormal laminated or folial pattern at MRI so that a pathological examination was necessary. Also, several reports showed that medulloblastoma could mimic LDD [12-14]. A very rare entity, Rosai-Dorfman granuloma, has been reported as a differential diagnosis of LDD by Johnston et al [15].…”
Section: Discussionmentioning
confidence: 99%