Infiltrats leucémiques choriorétiniens compliqués d’un décollement séreux rétinien dans une leucémie aiguë lymphoblastique pré-B

Dambricourt, L.; Sampo, M.; Levy, Norman S.; Arnould, Thomas; Yin, G. Ho Wang; Denis, D.

doi:10.1016/j.jfo.2018.12.011

Cited by 4 publications

(4 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Exudative RD is a relatively rare manifestation of leukemia and could be easily misdiagnosed as VKH, especially in patients who exhibit neurological manifestations and integument signs. 4 , 7 AlZamil 8 reported VKH-like RD in a patient who was eventually diagnosed with acute lymphocytic leukemia; prodromal symptoms might thus lead to misdiagnosis of VKH. Chawla et al.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Acute lymphocytic leukemia with initial manifestation of serous retinal detachment and choroidal thickening: case report and literature review

et al. 2021

View full text Add to dashboard Cite

This report describes a patient who had acute lymphocytic leukemia with exudative retinal detachment (RD), which mimicked Vogt–Koyanagi–Harada disease (VKH). A 61-year-old woman presented with painless loss of vision in the left eye. Fundus examination revealed RD in her left eye. B-scan ultrasonography confirmed localized RD and choroidal thickening. Fundus fluorescein angiography revealed stippled pinpoint hyperfluorescence in the upper macula. One week later, reduced visual acuity was noted in the right eye. B-scan ultrasonography and optical coherence tomography revealed serous RD in both eyes. A provisional diagnosis of VKH was made. However, subsequent hematologic analysis detected an extremely high leukocyte count. Elevated numbers of leukocytes and tumor cells were found in cerebrospinal fluid. Bone marrow biopsy revealed 77% primary atypical blood cells, 89% of which were immature lymphocytes. The patient was subsequently diagnosed with acute lymphocytic leukemia and transferred to the Department of Hematology. However, the patient and her family refused chemotherapy; she eventually died. Our findings suggest that exudative RD, similar to VKH, could be a sign of leukemia. Pinpoint hyperfluorescence leakage is important for differential diagnosis, particularly with respect to VKH.

show abstract

Section: Discussionmentioning

confidence: 99%

“…However, exudative RD may also precede the diagnosis of leukemia or occur during the course of the disease. 4 …”

Section: Introductionmentioning

confidence: 99%

Acute lymphocytic leukemia with initial manifestation of serous retinal detachment and choroidal thickening: case report and literature review

et al. 2021

View full text Add to dashboard Cite

show abstract

“…L'atteinte ophtalmologique au cours de la leucémie aigue myéloblastique (LMA) et lymphoblastique (LLA) est souvent présente à la phase terminale de la maladie [4]. Toutes les structures oculaires (la conjonctive, le nerf optique la choroïde et la rétine) peuvent être infiltrées [5]. L'infiltration orbitaire est un signe de mauvais pronostic [4].…”

Section: Discussionunclassified

“…La prise en charge thérapeutique des atteintes orbitaires liées aux maladies myeloprolifératives (le sarcome granulocytaire ou le plasmocytome) nécessite une collaboration pluridisciplinaire. Elle repose sur une chimiothérapie par voie générale et parfois intrathécale associée à des allogreffes de cellules souches [5,7,8,10].…”

Section: Discussionunclassified

Les exophtalmies révélatrices d’une hémopathie maligne chez l’enfant à propos de trois cas

Kerrouche¹,

Boumedane

Bourouis³

2021

jfmo

View full text Add to dashboard Cite

The primary orbital location of a malignant hemopathyin children is unusual.Our aim was to orient the ophthalmologist and the pediatrician to a rare etiology of pediatric exophthalmos.We report the observations of three patients hospitalized for exophthalmos with a normal initial blood count but in whom the myelogram made the diagnosis of acute myeloid leukemia or plasmacytoma. Conclusion:The first orbital involvement in acute leukemia is called granulocytic sarcoma or chloroma. This diagnosis should be considered in the event of any tumoral proptosis and the myelogram should be part of the initial assessment even if the blood count is normal, because early treatment improves the functional and vital prognosis.

show abstract

Serous retinal detachment as a presenting sign of acute lymphoblastic leukemia: A case report and literature review

Pasricha

Callaway

Nguyen

et al. 2021

American Journal of Ophthalmology Case Reports

View full text Add to dashboard Cite

Infiltrats leucémiques choriorétiniens compliqués d’un décollement séreux rétinien dans une leucémie aiguë lymphoblastique pré-B

Cited by 4 publications

References 9 publications

Acute lymphocytic leukemia with initial manifestation of serous retinal detachment and choroidal thickening: case report and literature review

Acute lymphocytic leukemia with initial manifestation of serous retinal detachment and choroidal thickening: case report and literature review

Les exophtalmies révélatrices d’une hémopathie maligne chez l’enfant à propos de trois cas

Serous retinal detachment as a presenting sign of acute lymphoblastic leukemia: A case report and literature review

Contact Info

Product

Resources

About