Inflammatory myofibroblastic tumour of the colon: 2 case reports and a comprehensive review of the literature

Karaıslı, Serkan; Kamer, Erdinç; Ekıncı, Neşe; Cengız, Fevzi; Er, Ahmet; Peşkersoy, Mustafa

doi:10.1007/s00384-020-03522-0

Cited by 7 publications

(13 citation statements)

References 39 publications

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“…2,5 Recently, Karaisli et al assessed 60 patients with colonic IPTs and presented a comprehensive review of the literature. 10 In the literature review, a male predominance (24 males and 15 females) was reported. Age-specific analysis revealed the highest incidence rates in patients aged 0-18 years and 30-50 years.…”

Section: Discussionmentioning

confidence: 99%

“…Although its clinical symptoms are diverse depending on the location of the lesion, abdominal pain, a palpable mass, and occasionally intestinal obstruction are the most common signs and symptoms. 2 , 5 Recently, Karaisli et al 10 assessed 60 patients with colonic IPTs and presented a comprehensive review of the literature. In the literature review, a male predominance (24 males and 15 females) was reported.…”

Section: Discussionmentioning

confidence: 99%

“…Local recurrence was detected from 2 months to 74 months after surgery, but 83.3% of recurrences were confirmed within 18 months after surgery. 10 Therefore, close and regular follow-up according to surveillance guidelines for postoperative colorectal cancer is required for these patients.…”

Section: A B Cmentioning

confidence: 99%

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A large and pedunculated inflammatory pseudotumor with pseudosarcomatous change of the cecum mimicking a malignant polyp: a case report and literature review

Kim

Park

et al. 2023

Clin Endosc

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Inflammatory pseudotumor (IPT) is a rare benign tumor of unknown etiology that can occur in almost any organ system. It has neoplastic features such as local recurrence, invasive growth, and vascular invasion, leading to the possibility of malignant sarcomatous changes. The clinical presentations of colonic IPT may include abdominal pain, anemia, a palpable mass, and intestinal obstruction. A few cases of colonic IPT have been reported, but colonic IPT with pedunculated morphology is very rare. Furthermore, since it can mimic malignant polyps, understanding the endoscopic findings of colonic IPT is important for proper treatment. Herein, we present a case of colonic IPT with pseudosarcomatous changes, presenting as a large polyp, mimicking a malignant polyp in the cecum, along with a literature review. Clin Endosc 2021 Jul 19.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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A large and pedunculated inflammatory pseudotumor with pseudosarcomatous change of the cecum mimicking a malignant polyp: a case report and literature review

Kim

Park

et al. 2023

Clin Endosc

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“…The incidence of local recurrence is between 15 and 40% (31). Serkan Karaisli, Erdinc Kamer et al collected follow-up information of 49 colorectal IMT patients, of which 7 experienced relapse without metastasis (32). The recurrence rate is related to the size of the tumours and the abdominal location and is higher among elderly patients (3).…”

Section: Discussionmentioning

confidence: 99%

Case Report: Recurrence of Testicular Myofibroblastic Tumor After Surgery

Liu

Bai

et al. 2022

Front. Oncol.

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Inflammatory myofibroblastic tumour (IMT), also known as plasma cell granuloma (PCG) or inflammatory pseudotumour (IPT), is a distinctive, rarely metastasizing neoplasm composed of myofibroblastic and fibroblastic spindle cells accompanied by inflammatory infiltration of plasma cells, lymphocytes and/or eosinophils. IMT predominantly affects children and young adults, and the age at presentation ranges from 3 to 89 years. We present a very rare case of recurrent testicular IMT without ALK rearrangement. This case highlights the clinical characteristics and diagnostic factors associated with primary and recurrent foci of this rare tumour, along with key therapeutic approaches.

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“…Subsequently, approximately 60 cases of colorectal IMT have been documented in the literature [5] . The frequency of its occurrence was in the order of the ascending colon, transverse colon, cecum, sigmoid colon, descending colon, and rectum [5] …”

Section: Introductionmentioning

confidence: 99%

Rectal inflammatory myofibroblastic tumor

Joo

2021

Medicine

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Rationale:Rectal inflammatory myofibroblastic tumor (IMT) is an extremely rare mesenchymal tumor characterized by a mixture of spindle-shaped myofibroblasts or fibroblasts and inflammatory infiltration of lymphocytes and plasma cells. To date, only 8 cases of rectal IMT have been reported. Herein, we report an additional case of rectal IMT in a 28-year-old woman.Patient concerns:A 28-year-old woman presented with abdominal pain and hematochezia.Diagnoses:Colonoscopy showed a 3.0-cm subepithelial tumor with central ulceration, covered by white exudate in the rectum. Rectal magnetic resonance imaging revealed a 4.0 × 3.0-cm-sized well-defined subepithelial tumor in the right wall of the rectum, with suspicious right perirectal fat infiltration.Interventions:Laparoscopic anterior resection was performed. Microscopic examination of the surgical specimen revealed bland-looking spindle cells intermingled with lymphoplasma cells. Immunohistochemistry and fluorescence in situ hybridization showed anaplastic lymphoma kinase positivity and anaplastic lymphoma kinase positivity rearrangement. Rectal IMT was confirmed based on histological, immunohistochemical, and fluorescence in situ hybridization findings. The patient was doing well without evidence of tumor recurrence 1 year after the surgery.Lessons:Rectal IMT, despite its rarity, should be considered in the differential diagnosis of rectal cancer. Second, an accurate histopathologic diagnosis and complete surgical resection can be the most important approaches to offer a chance for the cure of rectal IMT.

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Inflammatory myofibroblastic tumour of the colon: 2 case reports and a comprehensive review of the literature

Cited by 7 publications

References 39 publications

A large and pedunculated inflammatory pseudotumor with pseudosarcomatous change of the cecum mimicking a malignant polyp: a case report and literature review

A large and pedunculated inflammatory pseudotumor with pseudosarcomatous change of the cecum mimicking a malignant polyp: a case report and literature review

Case Report: Recurrence of Testicular Myofibroblastic Tumor After Surgery

Rectal inflammatory myofibroblastic tumor

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