Inflammatory Response of Channel Catfish to Abdominal Implants: A Histological and Ultrastructural Study

Abstract

Channel catfish Ictaluruspunctatus encapsulated implanted dummy transmitters in fibrous granulation tissue. Thirteen to 23 d after surgery, the fibrous capsules, 0.1-2.0 mm thick, contained numerous elongate fibroblasts (myofibroblasts) and dense collagen fibers oriented parallel to the transmitter surface. Cell types in the fibrous capsule identified with light and electron microscopy included red blood cells, endothelial cells, vascular pericytes, tissue lymphocytes, tissue and circulating neutrophils, circulating eosinophils, macrophages with ingested red blood cells, and fibroblasts with numerous intermediate filaments. The high concentration of actin in the fibroblasts, demonstrated by immunoperoxidase techniques, identified these cells as myofibroblasts. Based upon differential cell counts, macrophage concentration was higher and myofibroblast concentration was lower in the capsule area adjacent to the transmitter than at the exterior of the fibrous capsule. When a transmitter was expelled through the original abdominal incision to the environment or through the intestinal wall to the intestinal lumen, significant changes in cell numbers occurred in the fibrous capsule but only in the portion newly exposed to the environment or lumen. Lymphocyte and macrophage concentration increased after exposure to intestinal contents, whereas exposure to the external environment resulted in the formation of multinucleate giant cells.

Vertical movements of bigeye tuna (Thunnus obesus) associated with islands, buoys, and seamounts near the main Hawaiian Islands from archival tagging data

“…In these two individuals, we found the tags to be completely walled‐off from the peritoneal cavity and to be surrounded on the body surface with substantial areas of inflamed and necrotic tissue. These observations may indicate a possible route of tag loss through the ventral body wall as has been described in other fish species (Marty and Summerfelt, 1988). During necropsy of Fish 309, which had been at liberty for 1 year, we likewise found the tag body completely sealed off from the peritoneal cavity.…”

Structure and Biocompatibility of an Injectable Bone Regeneration Composite

“…4d. It was reported that, as a consequence of macrophage-biomaterial interaction, there is a fusion of adherent macrophages, leading to formation of multinucleated foreign body cells (FBGC) on the biomaterial surfaces [59][60][61]. This process is accompanied by FBGC-mediated biomaterial degradation [62].…”

Common carp tissue reactions to surgically implanted radio tags with external antennas

“…The granulation tissue resembled a classical foreign body reaction (Coleman et al , 1974). Marty & Summerfelt (1988) and Lucas (1989) described the histology of a similar capsule in channel catfish Ictalurus punctatus (Rafinesque) and rainbow trout Oncorhynchus mykiss (Walbaum), respectively. Adhesion of the granulation tissue to tissue of adjacent organs (intestine, liver) occurred in all mirror carp examined (Fig.…”