Influence of anion substitution on the crystal structure and color properties of copper-doped strontium hydroxyapatite

Pogosova, Mariam A.; González, Lissette

doi:10.1016/j.ceramint.2018.07.307

Cited by 14 publications

(6 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The doping of additives with low ionic radii to hydroxyapatite decreases the lattice parameters, while additives with high ionic radii increase these parameters [ 27 , 50 ]. In the literature, the average values of the lattice parameters of doped and un-doped strontium apatite are a = b = 9.775 Å and c = 7.269 Å [ 27 , 43 , 56 , 57 , 60 , 61 , 62 ]. In our study, these values were 9.738 Å and 7.254 Å for a = b and c, respectively.…”

Section: Discussionmentioning

confidence: 99%

In Vivo Evaluation of the Effects of B-Doped Strontium Apatite Nanoparticles Produced by Hydrothermal Method on Bone Repair

Öztekin

Gürgenç

Dündar

et al. 2022

JFB

View full text Add to dashboard Cite

In the present study, the structural, morphological, and in vivo biocompatibility of un-doped and boron (B)-doped strontium apatite (SrAp) nanoparticles were investigated. Biomaterials were fabricated using the hydrothermal process. The structural and morphological characterizations of the fabricated nanoparticles were performed by XRD, FT-IR, FE-SEM, and EDX. Their biocompatibility was investigated by placing them in defects in rat tibiae in vivo. The un-doped and B-doped SrAp nanoparticles were successfully fabricated. The produced nanoparticles were in the shape of nano-rods, and the dimensions of the nano-rods decreased as the B ratio increased. It was observed that the structural and morphological properties of strontium apatite nanoparticles were affected by the contribution of B. A stoichiometric Sr/P ratio of 1.67 was reached in the 5% B-doped sample (1.68). The average crystallite sizes were 34.94 nm, 39.70 nm, 44.93 nm, and 48.23 nm in un-doped, 1% B-doped, 5% B-doped, and 10% B-doped samples, respectively. The results of the in vivo experiment revealed that the new bone formation and osteoblast density were higher in the groups with SrAp nanoparticles doped with different concentrations of B than in the control group, in which the open defects were untreated. It was observed that this biocompatibility and the new bone formation were especially elevated in the B groups, which added high levels of strontium were added. The osteoblast density was higher in the group in which the strontium element was placed in the opened bone defect compared with the control group. However, although new bone formation was slightly higher in the strontium group than in the control group, the difference was not statistically significant. Furthermore, the strontium group had the highest amount of fibrotic tissue formation. The produced nanoparticles can be used in dental and orthopedic applications as biomaterials.

show abstract

Section: Discussionmentioning

confidence: 99%

In Vivo Evaluation of the Effects of B-Doped Strontium Apatite Nanoparticles Produced by Hydrothermal Method on Bone Repair

Öztekin

Gürgenç

Dündar

et al. 2022

JFB

View full text Add to dashboard Cite

show abstract

“…Apatite-type materials can be applied in many industrial fields, e.g., as sorbents, biocompatible and biodegradable materials for bone and teeth reconstruction, catalysts, materials for the wastewater treatment, fertilizers, and luminescent materials [ 1 , 2 ]. Hydroxyapatite (Ca 10 (PO 4 ) 6 (OH) 2 —abbr.…”

Section: Introductionmentioning

confidence: 99%

“…However, copper ions may have potentially toxic effects at higher amount in human beings due to their ability to generate ROSs (Reactive Oxygen Species). On the other hand, recent studies have shown that copper-doped apatite-type materials are very promising as a new kind of ow-toxic pigment that can be used in the paint and varnish industry [ 1 , 15 , 16 , 17 , 18 ].…”

Section: Introductionmentioning

confidence: 99%

Quenching of the Eu3+ Luminescence by Cu2+ Ions in the Nanosized Hydroxyapatite Designed for Future Bio-Detection

et al. 2021

View full text Add to dashboard Cite

The hydroxyapatite nanopowders of the Eu3+-doped, Cu2+-doped, and Eu3+/Cu2+-co-doped Ca10(PO4)6(OH)2 were prepared by a microwave-assisted hydrothermal method. The structural and morphological properties of the products were investigated by X-ray powder diffraction (XRD), transmission electron microscopy techniques (TEM), and infrared spectroscopy (FT-IR). The average crystal size and the unit cell parameters were calculated by a Rietveld refinement tool. The absorption, emission excitation, emission, and luminescence decay time were recorded and studied in detail. The 5D0 → 7F2 transition is the most intense transition. The Eu3+ ions occupied two independent crystallographic sites in these materials exhibited in emission spectra: one Ca(1) site with C3 symmetry and one Ca(2) sites with Cs symmetry. The Eu3+ emission is strongly quenched by Cu2+ ions, and the luminescence decay time is much shorter in the case of Eu3+/Cu2+ co-doped materials than in Eu3+-doped materials. The luminescence quenching mechanism as well as the schematic energy level diagram showing the Eu3+ emission quenching mechanism using Cu2+ ions are proposed. The electron paramagnetic resonance (EPR) technique revealed the existence of at least two different coordination environments for copper(II) ion.

show abstract

“…Gd-dependent blue emission was observed on selenium (Se) and gadolinium (Gd) dual ions doped HAp nanoparticles under ultraviolet (UV) irradiation [60]. Copper-doped Sr-HAp was prepared by solid-state reaction Sr 10 (VO 4 ) 6-x (PO 4 ) x O 2 Cu y H 2-y-δ (x = 0-6; y = 0-0.24) as the x value decreases; copper-doped samples show intense blue emission [61]. In most of the cases, the PL emission was reduced due to the concentration quenching and non-radiative recombination of electron and hole pairs which evidently showed the variation of active centers in the matrix.…”

Section: Introductionmentioning

confidence: 99%

Impact of Dopants on the Electrical and Optical Properties of Hydroxyapatite

Arul¹,

Ramya²,

Kalkura³

2020

Biomaterials

View full text Add to dashboard Cite

This chapter deals with the effect of alternating electrical current on hydroxyapatite [HAp, Ca10(PO4)6(OH)2] and doped HAp along with their optical response and the processes involved. The dielectric constant, permittivity and ac conductivity were analyzed to have an insight into the surface charge polarization phenomenon. Further, the magnitude and the polarity of the surface charges, microstructure, and phases also play significant role in the cell proliferation and growth on the implants. Besides, the mechanism behind the electrical properties and the healing of bone fracture are discussed. The influence of various dopants on the optical properties of HAp viz., absorbance, transmission, band gaps and defects energy levels are analyzed along with the photoluminescence and excitation independent emission. In the future outlook, the analysis of effect of doping is summarized and its impact on the next generation biomaterials are elucidated.

show abstract

Influence of anion substitution on the crystal structure and color properties of copper-doped strontium hydroxyapatite

Cited by 14 publications

References 40 publications

In Vivo Evaluation of the Effects of B-Doped Strontium Apatite Nanoparticles Produced by Hydrothermal Method on Bone Repair

In Vivo Evaluation of the Effects of B-Doped Strontium Apatite Nanoparticles Produced by Hydrothermal Method on Bone Repair

Quenching of the Eu3+ Luminescence by Cu2+ Ions in the Nanosized Hydroxyapatite Designed for Future Bio-Detection

Impact of Dopants on the Electrical and Optical Properties of Hydroxyapatite

Contact Info

Product

Resources

About