Influence of biological lubricant on the morphology of UHMWPE wear particles generated with microfabricated surface textures

Association of polyethylene friction and thermal unfolding of interfacial albumin molecules

“…This accomplishment enabled the bioactivity evaluation of different sizes and shapes of UHMWPE wear particles [24]. The influence of biological lubricant on the morphology of UHMWPE wear particles with surface textures have been reported [22]. From an engineering viewpoint, synovial fluid can be viewed as a lubricant containing albumin proteins, globulin proteins, lipids, hyaluronic acid, etc.…”

“…Typical pin-on-disk wear tests were also performed to investigate the effect of biological lubricants on the wear rate of UHMWPE [18][19][20]. Fang et al [21][22][23] further designed an accelerated wear testing procedure to compare the wear of UHMWPE under different biological lubricants. This accomplishment enabled the bioactivity evaluation of different sizes and shapes of UHMWPE wear particles [24].…”

Biomechanical Properties of Dispersep Article Reinforced Polymer Composites on Ultrahigh Molecular Weight Polyethylene (UHMWPE)

“…Priority of polymers, in particular UHMWPE to be applied as medical implant materials, is due to their proximity to the biological tissues by physical and mechanical properties [1][2][3][4][5]. The book [6], which contains the most complete information on the use of UHMWPE in medical practice, is focused on improving tribological properties of UHMWPE by ionizing radiation treatment.…”

Exploration of the size, shape and abundance of UHMWPE wear particles using atomic force microscopy

“…Since the size and geometry of the polyethylene wear particles may be expected to influence their biological activity, a large number of authors have characterised the diameter, shape and abundance (quantity) of particles generated in knee prostheses by extracting these particles in vitro and in vivo [5][6][7][8][9][10]. The bioactivity of different particle sizes has also been studied.…”

“…Different authors give varying size ranges for the most biologically active particles (0.1-10 m [5,6], 0.3-10 m [7], 0.24-0.45 m [8]). Irregularly shaped particles have been found to be more biological reactive than regularly shaped ones [9,10].…”