Influence of Body Mass Index, Surgical Approach and Lymphadenectomy on the Development of Symptomatic Lymphoceles after Radical Prostatectomy

Mundhenk, Jens; Hennenlotter, Joerg; Alloussi, Saladin Mahmud Helmut; Selbherr, D.; Martzog, J.C.; Todenhöfer, Tilman; Kruck, Stephan; Schwentner, Christian; Stenzl, Arnulf; Schilling, David

doi:10.1159/000347043

Cited by 15 publications

(19 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Our data did not support this hypothesis. A number of other authors also couldn't find any influence of age [20,26,27] .…”

Section: Discussionmentioning

confidence: 90%

“…Mundhenk et al reported that the lymphocele-positive cohort had a significantly higher BMI than their lymphocele-negative counterparts [20] . This is the only study so far to show this connection.…”

Section: Discussionmentioning

confidence: 99%

“…It is commonly accepted that the incidence is higher in cases of extended lymph node dissection [20,24,25] . The risk seems to be increased by 2-5% with every additional lymph node removed [24,26] .…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Lymphoceles Post-Radical Retropubic Prostatectomy: A Retrospective Evaluation of Epidemiology, Risk Factors and Outcome

Heers¹,

Laumeier²,

Olbert³

et al. 2015

Urol Int

View full text Add to dashboard Cite

Introduction: We aimed at evaluating the incidence of lymphoceles, a common complication after radical retropubic prostatectomy (RRP), at a high volume centre, define risk factors and assess the clinical outcome. Materials and Methods: 454 patients receiving RRP and pelvic lymph node dissection were assessed for postoperative lymphoceles using the ultrasound method. Findings were correlated to clinical parameters from a database (age, BMI, initial PSA, number of lymph nodes removed, prostate weight, duration of surgery, hospital stay, duration of catheterisation) and possible unconventional risk factors using meteorological data. Results: Overall, 15.4% developed a lymphocele, 2.6% had a symptomatic lymphocele requiring treatment. The mean size of the lymphoceles requiring treatment was significantly higher (400 vs. 115 ml). Patients with lymphocele stayed longer in hospital. No correlation could be found between the clinical parameters and the risk for lymphoceles. Functional results in terms of urinary continence were similar. The assessment of meteorological risk factors showed a correlation of lymphoceles with air humidity. Conclusion: Lymphoceles are common after RRP, but few cases require intervention. There is no reliable clinical predictor for the risk of lymphocele development. Data sets have been published suggesting several risk factors but may be subject to statistical error like in the case of the meteorological predictors in this study.

show abstract

“…Our data did not support this hypothesis. A number of other authors also couldn't find any influence of age [20,26,27] .…”

Section: Discussionmentioning

confidence: 90%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Lymphoceles Post-Radical Retropubic Prostatectomy: A Retrospective Evaluation of Epidemiology, Risk Factors and Outcome

Heers¹,

Laumeier²,

Olbert³

et al. 2015

Urol Int

View full text Add to dashboard Cite

show abstract

“…To be more representative for patients undergoing RP in Tyrol, a multicentre study approach should be considered. Additionally, an assessment of further complications of RP could be done [34]. Finally, our study does neither differentiate between different surgical approaches for RP (i.e., open, laparoscopic and robot-assisted) nor compare the number to patients with prostate cancer not undergoing RP or patients who are candidates for active surveillance [35].…”

Section: Discussionmentioning

confidence: 99%

Patient-Reported Urinary Incontinence and Erectile Dysfunction Following Radical Prostatectomy: Results from the European Prostate Centre Innsbruck

et al. 2015

View full text Add to dashboard Cite

Introduction: Urinary and erectile functions were assessed by using self-administered validated questionnaires in patients undergoing radical prostatectomy. Materials and Methods: In a prospective observational study, a total of 253 consecutive patients diagnosed with clinically localised prostate cancer between 2008 and 2009 at the European Prostate Centre Innsbruck were included. Patient-reported outcomes were assessed before radical prostatectomy and 12 months postoperatively using the validated International Consultation on Incontinence Questionnaire (ICIQ) and the International Index of Erectile Function (IIEF). The Wilcoxon signed-rank test and Chi square statistics were used for analysis. Results: The study showed that before radical prostatectomy, urinary incontinence of various severity grades was reported in 18.8, postoperatively in 63.0% (p < 0.001) and erectile dysfunction of various degrees was reported in 39.6 at baseline compared to 80.1% 12 months postoperatively (p < 0.001). Conclusions: This study suggests that radical prostatectomy is associated with a significantly increased risk of urinary incontinence and erectile dysfunction 12 months postoperatively.

show abstract

“…Its potential link to prostate cancer (PCa), which is the most common malignancy in men in developed countries and the second most common worldwide, has attracted many clinicians' attention [8,9,10,11]. As a result, a large body of literature has been recently published, with three quarters of the world's publications written over the last decade [12].…”

Section: Introductionmentioning

confidence: 99%

Obesity and Prostate Cancer Incidence and Mortality: A Systematic Review of Prospective Cohort Studies

et al. 2013

View full text Add to dashboard Cite

Background: There has been a large body of research on obesity and the risk of prostate cancer (PCa) that has been published recently. However, the epidemiological evidence for such an association has not been consistent. This may be attributed to the nature of case-control and retrospective studies, which generally are more prone to biases. Therefore, we conducted a systematic review of prospective cohort studies to assess the association between obesity and the risk of PCa incidence and death. Methods: A search of the PubMed database and references of published studies (from inception until March 2013) was conducted. Twenty-three eligible studies were identified and included in the systematic review. Results: The evidence from the prospective cohort studies linking obesity with PCa incidence has not been consistent. However, cumulative data is compelling for a strong positive association between obesity and fatal PCa. Conclusions: Obesity is a significant diet-related risk factor for fatal PCa. Further well-constructed, large cohort studies on the potential association between obesity and PCa, as well as on underlying mechanisms, are needed.

show abstract

Influence of Body Mass Index, Surgical Approach and Lymphadenectomy on the Development of Symptomatic Lymphoceles after Radical Prostatectomy

Cited by 15 publications

References 25 publications

Lymphoceles Post-Radical Retropubic Prostatectomy: A Retrospective Evaluation of Epidemiology, Risk Factors and Outcome

Lymphoceles Post-Radical Retropubic Prostatectomy: A Retrospective Evaluation of Epidemiology, Risk Factors and Outcome

Patient-Reported Urinary Incontinence and Erectile Dysfunction Following Radical Prostatectomy: Results from the European Prostate Centre Innsbruck

Obesity and Prostate Cancer Incidence and Mortality: A Systematic Review of Prospective Cohort Studies

Contact Info

Product

Resources

About