Influence of calcium (0.6 or 1.2%) and phosphorus (0.3 or 0.6%) content and ratio on the formation of urolithogenic compounds in the urine of Boer-cross goats fed high-concentrate diets

Freeman, S R; Poore, M. H.; Young, Gabrielle; Anderson, Kevin L.

doi:10.1016/j.smallrumres.2010.05.007

Cited by 10 publications

(14 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Detectou-se necrose tubular leve e moderada em 20/40 ovinos do grupo CA e em 16/20 cordeiros do grupo-controle. A deposição de restos celulares é um fator extremamente importante para a formação do núcleo orgâ-nico de urólito (Freeman et al 2010).…”

Section: Urináliseunclassified

“…Para isso, deve-se conhecer a composição química dos urólitos e corrigir todos os possíveis fatores que podem estar relacionados com sua formação (Freeman et al 2010, Sun et al 2010. Entre os métodos de prevenção, a acidificação urinária com cloreto de amônio (CA) é uma alternativa eficiente (Stewart et al 1991, Mavangira et al 2010, Ferreira et al 2014a).…”

Section: Introductionunclassified

See 1 more Smart Citation

Avaliação clínica, laboratorial e anatomopatológica do sistema urinário de ovinos confinados com ou sem suplementação de cloreto de amônio

et al. 2016

View full text Add to dashboard Cite

Resumo: A acidificação urinária com cloreto de amônio (CA) é um método preventivo eficiente em urolitíase obstrutiva em ovinos. Os objetivos deste estudo com ovinos confinados, que receberam dieta concentrada com elevado teor proteico, foram: verificar o efeito da dieta sobre a formação de urólitos e o desenvolvimento da doença; analisar as características macroscópicas e histopatológicas do sistema urinário; relacionar os achados clínicos, laboratoriais e necroscópicos com a presença de urólitos. Utilizaram-se 60 ovinos machos: grupo CA (n=40), 400 mg/kg CA/dia, tratados via oral, por 42 dias consecutivos; grupo-controle (n=20), não tratado. Determinaram-se sete momentos de colheita de amostras com intervalos de sete dias, no total de 56 dias de confinamento. Encontraram-se microcálculos na pelve renal em cinco animais de ambos os grupos. As lesões renais microscópicas mais relevantes foram congestão vascular e necrose tubular. Concluiu-se que a dieta rica em concentrado provocou lesão renal em ambos os grupos, embora sem alterar a função renal, o que foi comprovado em testes pela ureia e creatinina séricas. O cloreto de amônio fornecido ao grupo CA não impediu a calculogênese, mas reduziu sua prevalência em relação ao grupo-controle. Os ovinos do grupo-controle tiveram maior comprometimento renal, pela alta incidência de cristalúria e pela necrose tubular, induzidas pelo consumo da dieta rica em grãos.

show abstract

Section: Urináliseunclassified

Section: Introductionunclassified

Avaliação clínica, laboratorial e anatomopatológica do sistema urinário de ovinos confinados com ou sem suplementação de cloreto de amônio

et al. 2016

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 99%

“…Dietary treatment did not affect the extent of the increase. A majority of the crystals counted were visually identified, by the shape of the crystals according to Freeman et al (2010), as Ca phosphate. In a recent study determining the formation of urolithogenic compound in Boer goats when fed differing Ca to P ratios and levels, it was reported that the interactions of multiple minerals, not just Ca and P in the diet, influenced crystal and calculi formation (Freeman et al, 2010).…”

Section: Urine Mineral Concentrations and Crystal Scoresmentioning

confidence: 99%

“…A majority of the crystals counted were visually identified, by the shape of the crystals according to Freeman et al (2010), as Ca phosphate. In a recent study determining the formation of urolithogenic compound in Boer goats when fed differing Ca to P ratios and levels, it was reported that the interactions of multiple minerals, not just Ca and P in the diet, influenced crystal and calculi formation (Freeman et al, 2010). In the present study, urine pH was higher for the goats fed the 20P diets and for the goats fed the WH complete pelleted feed; however, all goats had alkaline urine (pH 8.44-8.92), which is conducive to the development of magnesium ammonium phosphate and Ca phosphate uroliths (Bartges et al, 1999).…”

Section: Urine Mineral Concentrations and Crystal Scoresmentioning

confidence: 99%

See 1 more Smart Citation

Impact of two types of complete pelleted, wild ungulate feeds and two pelleted feed to hay ratios on the development of urolithogenic compounds in meat goats as a model for giraffes

Sullivan

Freeman

Heugten

et al. 2012

Animal Physiology Nutrition

View full text Add to dashboard Cite

Urolith formation has been documented in giraffes and goats. As research in giraffes poses logistical challenges, 16 buck goats were used as a model. The impact of two commercially available, pelleted feeds used for giraffes, ADF-16 and Wild Herbivore (WH), as well as the impact of alfalfa hay and pellet proportions (20% hay:80% pellets, 80P or 80% hay:20% pellet, 20P) on the formation of urolithogenic precursors in goat urine was accomplished in a 2 × 2 factorial balance study. Complete diets contained 0.60, 0.32, 0.35 and 0.26% phosphorus (P) with calcium:P ratios of 1.60, 4.16, 3.06 and 5.23, for 80P-ADF-16, 20P-ADF-16, 80P-WH and 20P-WH respectively. Total faeces and urine were collected over two 5-day periods to assess N and mineral balance. Fresh urine samples were collected and evaluated microscopically for urolithic crystal content. Urinary nitrogen (N) was lower and N retention was higher in goats fed 80P diets (p < 0.05). Intake of P was greatest for goats fed 80P-ADF-16; however, urinary P excretion and P retention were not affected by treatment. Crystal scores were higher in animals receiving 80P diets (p = 0.08), with crystals being composed predominantly of calcium phosphate. Urine pH was alkaline (>8) for all treatments. Urinary P concentration, a risk factor for urolithiasis, was highest (p ≤ 0.06) in the 80P-ADF-16 treatment (0.38 vs. 0.01, 0.02 and 0.04 mg/dl for 20P-ADF-16, 80P-WH and 20P-WH respectively), reflecting its highest dietary P level. Further investigation is recommended to determine the long-term effects of these diets on urolithogenic compound formation.

show abstract

Water intake and ingestive behavior of sheep fed diets based on silages of cactus pear and tropical forages

Silva

Araújo

Santos

et al. 2021

Trop Anim Health Prod

View full text Add to dashboard Cite

The objective was to evaluate the water intake and ingestive behavior of sheep fed diets containing silages of cactus pear combined with tropical forages. Forty sheep without defined breed, intact, with initial average weight of 22.65 ± 1.01 kg were distributed in a completely randomized design with 5 treatments and 8 replications. The experimental diets consisted of cactus pear silage (CPS), cactus pear + buffel grass silage (CPBS), cactus pear + gliricidia silage (CPGS), cactus pear + pornunça silage (CPPS), and corn silage (CS). CPGS provided higher water intake via food, total water intake, metabolic water, and excretion via feces and urine (P < 0.05). Animals that received diets containing CS showed higher water intake via drinking fountain, less efficient feeding and rumination of dry matter, less efficient rumination of neutral detergent fiber, grams of dry matter per cud, grams of neutral detergent fiber per cud, and the shortest average time spent in chewing per cud (P < 0.05). CPGS, CPPS, and CS provided longer times for rumination and numbers of cuds per day (P < 0.05). CPS showed animals spending more time in idleness, lower quantity of cuds per minute, higher concentration of crystals in urine, with a higher frequency of ammonia-magnesium phosphate and calcium oxalate. Silages based on cactus pear are an alternative to the supply of water via food for sheep in semi-arid.

show abstract

Influence of calcium (0.6 or 1.2%) and phosphorus (0.3 or 0.6%) content and ratio on the formation of urolithogenic compounds in the urine of Boer-cross goats fed high-concentrate diets

Cited by 10 publications

References 20 publications

Avaliação clínica, laboratorial e anatomopatológica do sistema urinário de ovinos confinados com ou sem suplementação de cloreto de amônio

Avaliação clínica, laboratorial e anatomopatológica do sistema urinário de ovinos confinados com ou sem suplementação de cloreto de amônio

Impact of two types of complete pelleted, wild ungulate feeds and two pelleted feed to hay ratios on the development of urolithogenic compounds in meat goats as a model for giraffes

Water intake and ingestive behavior of sheep fed diets based on silages of cactus pear and tropical forages

Contact Info

Product

Resources

About