“…This sealer is composed of salicylate resin, resin diluent, natural resin, bismuth oxide, silica nanoparticles, and MTA. Its physical properties (11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23) and biocompatibility (24,25) are already known. Nonetheless, to date, no studies have been conducted to analyze histologically the effect of MTA Fillapex in direct contact with bone tissue.…”