Despite concerns about building dampness and children’ health, few studies have examined the effects of building energy efficiency standards. This study explored the connections between self‐reported household dampness and children’ adverse health outcomes across buildings corresponding to construction periods (pre‐2001, 2001‐2010, post‐2010). Significant differences of dampness‐related indicators were found between buildings; the prevalence was remarkable in pre‐2001 buildings. The prevalence of lifetime‐ever doctor‐diagnosed diseases for children was significantly associated with building dampness (adjust odd ratios > 1), but was not affected by construction periods. The hygrothermal performance for a typical residence was simulated, varying in U‐values of envelopes and air change rates. The simulated performance improvement increased indoor temperatures in 2001‐2010 and post‐2010 buildings. The frequency with higher indoor relative humidity was higher in pre‐2001 buildings, leading to the highest values for maximum mold index (Mmax) on wall surface, especially in winter. Compared to buildings in 2001‐2010, increased insulation and lower air change rate led to a relatively higher relative humidity in post‐2010 buildings, adversely increasing the Mmax values. The findings addressed the positive and negative role of building standard development, which help suggesting appropriate environmental and design solutions to trade‐off energy savings and dampness/mold risk in residences.