The experiment was conducted in one of the special fields for the winter agricultural season 2020/2021 in Al-Qadisiyah province / Sumer-Al-Barakat sub-district, which is 17 km from the district, at 32.14 degrees north latitude and 44.99 degrees east longitude. To know the effect of spraying some nano-fertilizers and their combinations on the growth and yield of the fenugreek, the experiment was carried out according to a randomized complete block design with three replications. The experiment included 10 treatments (T1), the control treatment, spraying distilled water only, (T2) a balanced nano-NPK spraying at a concentration of 2 g L-1, (T3) adding NPK mineral fertilizer 200 kg ha-1, (T4) Spraying nano microelements 2 g L-1 + NPK mineral fertilizer, (T5) Spraying nano seaweed extract 2ml.L-1 + adding NPK mineral fertilizer, (T6) spraying nano NPK at a concentration of 2 g.L-1 + mineral NPK, (T7) Spraying nano micro-elements fertilizer at a concentration of 2 g L-1 + nano seaweed extract at a concentration of 2 ml L-1 + adding NPK mineral fertilizer, (T8) spraying nano micro-elements at a concentration of 2 g L-1 + nano NPK at a concentration of 2 g L-1 + adding NPK mineral fertilizer and (T9) spraying nano seaweed extract at a concentration of 2 ml L-1 + nano NPK at a concentration of 2 g L-1 + adding Mineral NPK fertilizer and (T10) spraying nano-micro elements 2 g. L-1 + nano seaweed extract 2 ml L-1 + NPK nano-concentration 2 g L-1 + adding NPK mineral fertilizer, the first spraying was done three times when the plants reached 6-8 leaves, the second and the third with an interval of 14 days between them. The results showed significantly excelled of plants treated with (T10) and the highest averages were achieved in the vegetative growth traits compared to the control treatment. It also produced the highest averages in all yield traits and its components, especially the fresh and dry leaf yield, and seed and oil yield, which amounted to 12.771, 1.442, 1.431, and 159.48 kg ha-1, respectively, compared with the control treatment, which produced 9.514, 1.163, 1.024 and 99.38 kg ha-1, respectively.